Background The efficacy of SARS-CoV-2 vaccines in preventing severe COVID-19 illness
and death is uncertain due to the rarity of data in individual trials. How well the antibody …

Knowing vaccine effectiveness (VE) against variants of concern (VOCs) in the real-world
setting is essential for public health decision-making. A systematic landscape of the VE …

Breakthrough infections by SARS-CoV-2 variants become the global challenge for
pandemic control. Previously, we developed the protein subunit vaccine ZF2001 based on …

The amino acid sequences of peptides determine their self-assembling properties. Accurate
prediction of peptidic hydrogel formation, however, remains a challenging task. This work …

New Immunogens Needed for Emerging Omicron Variants Emerging omicron subvariants
express additional spike mutations that escape detection by neutralizing antibodies elicited …

Although there was a global shortage of Covid-19 vaccines in 2021, by mid 2022, the
vaccine supply will no longer be a limiting factor in efforts to provide more equitable …

The ongoing global pandemic of coronavirus disease 2019 (COVID-19), caused by severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has caused devastating impacts …

Vaccines based on historical virus isolates provide limited protection from continuously
evolving RNA viruses, such as influenza viruses or coronaviruses, which occasionally spill …

Defending against future pandemics requires vaccine platforms that protect across a range
of related pathogens. Nanoscale patterning can be used to address this issue. Here, we …

COVID-19 vaccines have been developed to confer immunity against the SARS-CoV-2
infection. Prior to the pandemic of COVID-19 which started in March 2020, there was a well …