Scalable volumetric imaging for ultrahigh-speed brain mapping at synaptic resolution

H Wang, Q Zhu, L Ding, Y Shen, CY Yang… - National Science …, 2019 - academic.oup.com
The speed of high-resolution optical imaging has been a rate-limiting factor for meso-scale
mapping of brain structures and functional circuits, which is of fundamental importance for …

X-ray microscopy as an approach to increasing accuracy and efficiency of serial block-face imaging for correlated light and electron microscopy of biological …

EA Bushong, DD Johnson Jr, KY Kim… - Microscopy and …, 2015 - academic.oup.com
The recently developed three-dimensional electron microscopic (EM) method of serial block-
face scanning electron microscopy (SBEM) has rapidly established itself as a powerful …

Array tomography

I Wacker, RR Schroeder - Journal of microscopy, 2013 - Wiley Online Library
In array tomography ordered, ribbon‐like assemblies of ultrathin serial sections are
deposited on a solid substrate and imaged afterwards. The resulting images are then …

Multi-beam scanning electron microscopy for high-throughput imaging in connectomics research

AL Eberle, D Zeidler - Frontiers in neuroanatomy, 2018 - frontiersin.org
Major progress has been achieved in recent years in three-dimensional microscopy
techniques. This applies to the life sciences in general, but specifically the neuroscientific …

Optogenetic approaches for functional mouse brain mapping

DH Lim, J LeDue, MH Mohajerani, MP Vanni… - Frontiers in …, 2013 - frontiersin.org
To better understand the connectivity of the brain, it is important to map both structural and
functional connections between neurons and cortical regions. In recent years, a set of …

The anatomical problem posed by brain complexity and size: a potential solution

J DeFelipe - Frontiers in neuroanatomy, 2015 - frontiersin.org
Over the years the field of neuroanatomy has evolved considerably but unraveling the
extraordinary structural and functional complexity of the brain seems to be an unattainable …

A null model of the mouse whole-neocortex micro-connectome

MW Reimann, M Gevaert, Y Shi, H Lu… - Nature …, 2019 - nature.com
In connectomics, the study of the network structure of connected neurons, great advances
are being made on two different scales: that of macro-and meso-scale connectomics …

Synchronization dependent on spatial structures of a mesoscopic whole-brain network

H Choi, S Mihalas - PLoS computational biology, 2019 - journals.plos.org
Complex structural connectivity of the mammalian brain is believed to underlie the versatility
of neural computations. Many previous studies have investigated properties of small …

Sensitivity of laser speckle contrast imaging to flow perturbations in the cortex

MA Davis, L Gagnon, DA Boas… - Biomedical optics express, 2016 - opg.optica.org
Laser speckle contrast imaging has become a ubiquitous tool for imaging blood flow in a
variety of tissues. However, due to its widefield imaging nature, the measured speckle …

Relating network connectivity to dynamics: opportunities and challenges for theoretical neuroscience

C Curto, K Morrison - Current opinion in neurobiology, 2019 - Elsevier
Highlights•Relating network connectivity to dynamics poses a serious theoretical
challenge.•Network science concepts may have limited relevance in a neuroscience …