Isobaric labeling-based relative quantification in shotgun proteomics

N Rauniyar, JR Yates III - Journal of proteome research, 2014 - ACS Publications
Mass spectrometry plays a key role in relative quantitative comparisons of proteins in order
to understand their functional role in biological systems upon perturbation. In this review, we …

Analysis of the plasma proteome using iTRAQ and TMT‐based Isobaric labeling

R Moulder, SD Bhosale, DR Goodlett… - Mass spectrometry …, 2018 - Wiley Online Library
Over the past decade, chemical labeling with isobaric tandem mass tags, such as isobaric
tags for relative and absolute quantification reagents (iTRAQ) and tandem mass tag (TMT) …

Proteomic discovery of non-invasive biomarkers of localized prostate cancer using mass spectrometry

A Khoo, LY Liu, JO Nyalwidhe, OJ Semmes… - Nature Reviews …, 2021 - nature.com
Prostate cancer is the second most frequently diagnosed non-skin cancer in men worldwide.
Patient outcomes are remarkably heterogeneous and the best existing clinical prognostic …

Approaches to urinary detection of prostate cancer

JN Eskra, D Rabizadeh, CP Pavlovich… - Prostate cancer and …, 2019 - nature.com
Background Prostate cancer is the most common cancer in American men that ranges from
low risk states amenable to active surveillance to high-risk states that can be lethal …

Biomarkers that differentiate benign prostatic hyperplasia from prostate cancer: A literature review

CJ McNally, MW Ruddock, T Moore… - Cancer management …, 2020 - Taylor & Francis
Prediction of prostate cancer in primary care is typically based upon serum total prostate-
specific antigen (tPSA) and digital rectal examination results. However, these tests lack …

Prognostic value of serum alkaline phosphatase in the survival of prostate cancer: evidence from a meta-analysis

D Li, H Lv, X Hao, B Hu, Y Song - Cancer management and …, 2018 - Taylor & Francis
Background Many studies have evaluated the relationship between alkaline phosphatase
(ALP) and the prognosis for prostate cancer (PCa). But they have not reached a widespread …

[HTML][HTML] A new era of prostate cancer precision medicine

A Malik, S Srinivasan, J Batra - Frontiers in Oncology, 2019 - frontiersin.org
Prostate cancer is the second most common male cancer affecting Western society. Despite
substantial advances in the exploration of prostate cancer biomarkers and treatment …

Urinary biomarkers in prostate cancer detection and monitoring progression

D Wu, J Ni, J Beretov, P Cozzi, M Willcox… - Critical reviews in …, 2017 - Elsevier
Prostate cancer (CaP) is the most common cancer in men and the second leading cause of
cancer deaths in males in Australia. Although serum prostate-specific antigen (PSA) has …

[HTML][HTML] A Combined CRISP3 and SPINK1 prognostic grade in EPS-urine and establishment of models to predict prognosis of patients with prostate cancer

L Chen, E Zhang, J Guan, Z Chen, J Ye, W Liu… - Frontiers in …, 2022 - frontiersin.org
Background Prostate cancer (PCa) is characterized by significant heterogeneity. Thus, novel
prognostic indicators are required to improve prognosis and treatment. Methods Cysteine …

Identification of Urinary Biomarkers for Exercise‐Induced Immunosuppression by iTRAQ Proteomics

G Xu, W Lin, AJ McAinch, X Yan… - BioMed Research …, 2020 - Wiley Online Library
Purpose. To identify noninvasive immune biomarkers of exercise‐induced
immunosuppression using the iTRAQ proteomics technique. Methods. Fifteen healthy males …