Gastric cancer: epidemiology, risk factors, classification, genomic characteristics and treatment strategies

J Machlowska, J Baj, M Sitarz, R Maciejewski… - International journal of …, 2020 - mdpi.com
Gastric cancer (GC) is one of the most common malignancies worldwide and it is the fourth
leading cause of cancer-related death. GC is a multifactorial disease, where both …

Role of Flagella in the Pathogenesis of Helicobacter pylori

H Gu - Current microbiology, 2017 - Springer
This review aimed to investigate the role of Helicobacter pylori flagella on the pathogenicity
of this bacterium in humans. Helicobacter pylori is a flagellated pathogen that colonizes the …

Influence of Helicobacter pylori virulence factors CagA and VacA on pathogenesis of gastrointestinal disorders

S Nejati, A Karkhah, H Darvish, M Validi… - Microbial …, 2018 - Elsevier
Helicobacter Pylori (H. pylori) is a gram-negative bacteria infecting numerous people all
over the world. It has been established that H. pylori play an important role in pathogenesis …

The Role of Helicobacter pylori Neutrophil-Activating Protein in the Pathogenesis of H. pylori and Beyond: From a Virulence Factor to Therapeutic Targets and …

HW Fu, YC Lai - International Journal of Molecular Sciences, 2022 - mdpi.com
Helicobacter pylori neutrophil-activating protein (HP-NAP), a major virulence factor of H.
pylori, plays a role in bacterial protection and host inflammation. HP-NAP activates a variety …

The Clinical Importance of Campylobacter concisus and Other Human Hosted Campylobacter Species

F Liu, R Ma, Y Wang, L Zhang - Frontiers in cellular and infection …, 2018 - frontiersin.org
Historically, Campylobacteriosis has been considered to be zoonotic; the Campylobacter
species that cause human acute intestinal disease such as Campylobacter jejuni and …

Molecular Mechanisms of Antibiotic Resistance and Novel Treatment Strategies for Helicobacter pylori Infections

M Srisuphanunt, P Wilairatana, N Kooltheat… - Tropical Medicine and …, 2023 - mdpi.com
Helicobacter pylori infects approximately 50% of the world's population and is considered
the major etiological agent of severe gastric diseases, such as peptic ulcers and gastric …

Detection of Helicobacter pylori and its virulence genes (cagA, dupA, and vacA) among patients with gastroduodenal diseases in Chris Hani Baragwanath …

A Idowu, A Mzukwa, U Harrison, P Palamides… - BMC …, 2019 - Springer
Background The global prevalence of H. pylori approaches 50%, with prevalence rates
between 20 and 40% in developed countries and up to 90% in Africa and other developing …

Electrochemical Immunosensor for Detection of H. pylori Secretory Protein VacA on gC3N4/ZnO Nanocomposite-Modified Au Electrode

K Saxena, A Kumar, N Chauhan, M Khanuja… - ACS …, 2022 - ACS Publications
A g-C3N4/ZnO (graphitic carbon nitride/zinc oxide) nanocomposite-decorated gold
electrode was employed to design an antigen–antibody-based electrochemical biosensor to …

Helicobacter pylori and Gastric Cancer: Pathogenetic Mechanisms

S Salvatori, I Marafini, F Laudisi, G Monteleone… - International journal of …, 2023 - mdpi.com
Gastric cancer is the sixth most commonly diagnosed cancer and the fourth leading cause of
cancer death worldwide. Helicobacter pylori (H. pylori) is one of the main risk factors for this …

Epigenetic changes in gastric cancer induction by Helicobacter pylori

B Yousefi, M Mohammadlou… - Journal of cellular …, 2019 - Wiley Online Library
Epigenetic disorder mechanisms are one of the causes of cancer. The most important of
these changes is the DNA methylation, which leads to the spread of Helicobacter pylori and …