Modulation of NRF2/KEAP1 signaling in preeclampsia

G Tossetta, S Fantone, F Piani, C Crescimanno… - Cells, 2023 - mdpi.com
Placentation is a key and tightly regulated process that ensures the normal development of
the placenta and fetal growth. Preeclampsia (PE) is a hypertensive pregnancy-related …

Role of CD93 in Health and Disease

G Tossetta, F Piani, C Borghi, D Marzioni - Cells, 2023 - mdpi.com
CD93 (also known as complement protein 1 q subcomponent receptor C1qR1 or C1qRp), is
a transmembrane glycoprotein encoded by a gene located on 20p11. 21 and composed of …

Non-alcoholic fatty liver disease and gut microbial dysbiosis-underlying mechanisms and gut microbiota mediated treatment strategies

M Jayachandran, S Qu - Reviews in Endocrine and Metabolic Disorders, 2023 - Springer
Non-alcoholic fatty liver disease (NAFLD) is by far the most prevalent form of liver disease
worldwide. It's also the leading cause of liver-related hospitalizations and deaths …

Circulating microRNA as Biomarkers for Gestational Diabetes Mellitus—A Systematic Review and Meta-Analysis

S Dinesen, A El-Faitarouni, NLS Frisk… - International Journal of …, 2023 - mdpi.com
Gestational diabetes mellitus (GDM) is a severe pregnancy complication for both the woman
and the child. Women who suffer from GDM have a greater risk of developing Type 2 …

[HTML][HTML] Opportunities and barriers in omics-based biomarker discovery for steatotic liver diseases

M Thiele, IF Villesen, L Niu, S Johansen, K Sulek… - Journal of …, 2024 - Elsevier
The rising prevalence of liver diseases related to obesity and excessive use of alcohol is
fuelling an increasing demand for accurate biomarkers aimed at community screening …

Programming of cardiac metabolism by miR-15b-5p, a miRNA released in cardiac extracellular vesicles following ischemia-reperfusion injury

LC Pantaleão, E Loche, DS Fernandez-Twinn… - Molecular …, 2024 - Elsevier
Objective We investigated the potential involvement of miRNAs in the developmental
programming of cardiovascular diseases (CVD) by maternal obesity. Methods Serum …

Gut microbiota induced epigenetic modifications in the non‐alcoholic fatty liver disease pathogenesis

R Tang, R Liu, H Zha, Y Cheng… - Engineering in Life …, 2024 - Wiley Online Library
Non‐alcoholic fatty liver disease (NAFLD) represents a growing global health concern that
can lead to liver disease and cancer. It is characterized by an excessive accumulation of fat …

Extracellular Vesicles as Delivery Vehicles for Non-Coding RNAs: Potential Biomarkers for Chronic Liver Diseases

A Ferro, G Saccu, S Mattivi, A Gaido… - Biomolecules, 2024 - mdpi.com
In recent years, EVs have emerged as promising vehicles for coding and non-coding RNAs
(ncRNAs), which have demonstrated remarkable potential as biomarkers for various …

Comprehensive strategy for identifying extracellular vesicle surface proteins as biomarkers for non-alcoholic fatty liver disease

NA Garcia, M Mellergaard, H Gonzalez-King… - International Journal of …, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a liver disorder that has become a global health
concern due to its increasing prevalence. There is a need for reliable biomarkers to aid in …

Extracellular microRNAs in Relation to Weight Loss—A Systematic Review and Meta-Analysis

CHB Veie, IMT Nielsen, NLS Frisk, LT Dalgaard - Non-coding RNA, 2023 - mdpi.com
Obesity is an important risk factor for cardiovascular disease and type 2 diabetes mellitus.
Even a modest weight loss of 5–15% improves metabolic health, but circulating markers to …