Single-cell profiling methods have had a profound impact on the understanding of cellular
heterogeneity. While genomes and transcriptomes can be explored at the single-cell level …

Evolution has found countless ways to transport material across cells and cellular
compartments separated by membranes. Protein assemblies are the cornerstone for the …

Alditols, which have a sweet taste but produce much lower calories than natural sugars, are
widely used as artificial sweeteners. Alditols are the reduced forms of monosaccharide …

The nanopore is emerging as a means of single-molecule protein sensing. However,
proteins demonstrate different charge properties, which complicates the design of a sensor …

Natural herbs, which contain pharmacologically active compounds, have been used
historically as medicines. Conventionally, the analysis of chemical components in herbal …

Protein detection has wide-ranging implications in molecular diagnostics. Substantial
progress has been made in protein analytics using nanopores and the resistive-pulse …

The single‐molecule technique for investigation of an unlabeled protein in solution is very
attractive but with great challenges. Nanopore sensing as a label‐free tool can be used for …

Nanopores are versatile single-molecule sensors offering a simple label-free readout with
great sensitivity. We recently introduced the nanopore electro-osmotic trap (NEOtrap) which …

WD40 repeat proteins are frequently involved in processing cell signaling and scaffolding
large multi-subunit machineries. Despite their significance in physiological and disease-like …

Protein kinases play central role in cellular regulation by catalyzing the phosphorylation of
target proteins involved in complex physiological processes, achieved by their structural …