[HTML][HTML] The T cell immune response against SARS-CoV-2
P Moss - Nature immunology, 2022 - nature.com
The adaptive immune response is a major determinant of the clinical outcome after SARS-
CoV-2 infection and underpins vaccine efficacy. T cell responses develop early and …
CoV-2 infection and underpins vaccine efficacy. T cell responses develop early and …
[HTML][HTML] T cells in health and disease
L Sun, Y Su, A Jiao, X Wang, B Zhang - Signal transduction and …, 2023 - nature.com
T cells are crucial for immune functions to maintain health and prevent disease. T cell
development occurs in a stepwise process in the thymus and mainly generates CD4+ and …
development occurs in a stepwise process in the thymus and mainly generates CD4+ and …
[HTML][HTML] Multi-omics resolves a sharp disease-state shift between mild and moderate COVID-19
We present an integrated analysis of the clinical measurements, immune cells, and plasma
multi-omics of 139 COVID-19 patients representing all levels of disease severity, from serial …
multi-omics of 139 COVID-19 patients representing all levels of disease severity, from serial …
Association of psychiatric disorders with mortality among patients with COVID-19
K Nemani, C Li, M Olfson, EM Blessing… - JAMA …, 2021 - jamanetwork.com
Importance To date, the association of psychiatric diagnoses with mortality in patients
infected with coronavirus disease 2019 (COVID-19) has not been evaluated. Objective To …
infected with coronavirus disease 2019 (COVID-19) has not been evaluated. Objective To …
Association between mental health disorders and mortality among patients with COVID-19 in 7 countries: a systematic review and meta-analysis
G Fond, K Nemani, D Etchecopar-Etchart… - JAMA …, 2021 - jamanetwork.com
Importance Heterogeneous evidence exists for the association between COVID-19 and the
clinical outcomes of patients with mental health disorders. It remains unknown whether …
clinical outcomes of patients with mental health disorders. It remains unknown whether …
Senolytics reduce coronavirus-related mortality in old mice
INTRODUCTION The COVID-19 pandemic revealed enhanced vulnerability of the elderly
and chronically ill to adverse outcomes upon severe acute respiratory syndrome coronavirus …
and chronically ill to adverse outcomes upon severe acute respiratory syndrome coronavirus …
[HTML][HTML] Human umbilical cord-derived mesenchymal stem cell therapy in patients with COVID-19: a phase 1 clinical trial
F Meng, R Xu, S Wang, Z Xu, C Zhang, Y Li… - Signal transduction and …, 2020 - nature.com
No effective drug treatments are available for coronavirus disease 2019 (COVID-19). Host-
directed therapies targeting the underlying aberrant immune responses leading to …
directed therapies targeting the underlying aberrant immune responses leading to …
[HTML][HTML] Diabetes is most important cause for mortality in COVID-19 hospitalized patients: Systematic review and meta-analysis
The presence of SARS-CoV-2 was officially documented in Europe at the end of February
2020. Despite many observations, the real impact of COVID-19 in the European Union (EU) …
2020. Despite many observations, the real impact of COVID-19 in the European Union (EU) …
[HTML][HTML] Activation or exhaustion of CD8+ T cells in patients with COVID-19
In addition to CD4+ T cells and neutralizing antibodies, CD8+ T cells contribute to protective
immune responses against SARS-CoV-2 in patients with coronavirus disease 2019 (COVID …
immune responses against SARS-CoV-2 in patients with coronavirus disease 2019 (COVID …
Severely ill patients with COVID-19 display impaired exhaustion features in SARS-CoV-2–reactive CD8+ T cells
The molecular properties of CD8+ T cells that respond to SARS-CoV-2 infection are not fully
known. Here, we report on the single-cell transcriptomes of> 80,000 virus-reactive CD8+ T …
known. Here, we report on the single-cell transcriptomes of> 80,000 virus-reactive CD8+ T …