Background. Next‐generation sequencing methods have been developed and proposed to
investigate any query in genomics or clinical activity involving DNA. Technical advancement …

With fast development and wide applications of next‐generation sequencing (NGS)
technologies, genomic sequence information is within reach to aid the achievement of goals …

Long-read, single-molecule real-time (SMRT) sequencing is routinely used to finish
microbial genomes, but available assembly methods have not scaled well to larger …

High-throughput sequencing technology is rapidly improving in quality, speed and cost. It is
therefore becoming more widely used to study whole communities of prokaryotes in many …

Background The short reads output by first-and second-generation DNA sequencing
instruments cannot completely reconstruct microbial chromosomes. Therefore, most …

Next generation sequencing (NGS) technologies have impressively accelerated research in
biological science during the last years by enabling the production of large volumes of …

This book presents a series of chapters on the current knowledge with an emphasis on the
interactions of host animal with the microbes in the rumen. The whole content is divided into …

Transport of ions through pores in membranes is a process of fundamental importance to
cell biology. In living organisms, such transport is facilitated by ion channels that utilize the …

Nanopores are emerging as powerful tools for the detection and identification of
macromolecules in aqueous solution. In this review, we discuss the recent development of …

An inexpensive, reliable method for protein sequencing is essential to unraveling the
biological mechanisms governing cellular behavior and disease. Current protein …