H Yan, D Shao, YH Lao, M Li, H Hu… - Advanced …, 2019 - Wiley Online Library
Inflammation is ubiquitous in the body, triggering desirable immune response to defend against dangerous signals or instigating undesirable damage to cells and tissues to cause …
L Giovannelli, E Bari, C Jommi, F Tartara, D Armocida… - Bioactive Materials, 2023 - Elsevier
Neurodegenerative diseases represent a growing burden on healthcare systems worldwide. Mesenchymal stem cells (MSCs) have shown promise as a potential therapy due to their …
L Gaissmaier, M Elshiaty, P Christopoulos - Cells, 2020 - mdpi.com
Immune checkpoint inhibitors have redefined the treatment of cancer, but their efficacy depends critically on the presence of sufficient tumor-specific lymphocytes, and cellular …
E Seoane‐Vazquez, V Shukla… - EMBO molecular …, 2019 - embopress.org
Advanced therapy medicinal products (ATMPs), including gene therapy, cell therapy, and tissue engineering products, represent a paradigm shift in health care as they have great …
T cell activation is sensitive to the mechanical properties of an activating substrate. However, there are also contrasting results on how substrate stiffness affects T cell activation …
Background Although a preponderance of pre-clinical data demonstrates the immunosuppressive potential of mesenchymal stromal cells (MSCs), significant …
G Kim, JH Jeon, K Park, SW Kim, DH Kim, S Lee - Scientific Reports, 2022 - nature.com
Mesenchymal stem cells (MSCs) are increasingly used as regenerative therapies for patients in the preclinical and clinical phases of various diseases. However, the main …
Y Huang, X Gao, J Chen - Acta Pharmaceutica Sinica B, 2018 - Elsevier
Precise drug delivery to tumors with low system toxicity is one of the most important and challenging tasks for pharmaceutical researchers. Despite progress in the field of …
OF Garcia-Aponte, C Herwig, B Kozma - Journal of Biological Engineering, 2021 - Springer
Bioreactors are essential tools for the development of efficient and high-quality cell therapy products. However, their application is far from full potential, holding several challenges …