Perindopril is a long-acting, once-daily lipophilic angiotensin-converting enzyme inhibitor
with high tissue angiotensin-converting enzyme affinity, lowering angiotensin II and …

Volume 49, no. 5: May 2007 Annals of Emergency Medicine 627 were determined by the
committee members to represent some of the most important and controversial issues …

Background A drug-drug interaction (DDI) is defined as a drug effect modified by another
drug, which is very common in treating complex diseases such as cancer. Many studies …

Angiotensin-Converting enzyme (ACE) inhibitors are a heterogeneous class, varying in
pharmacologic properties, which have different therapeutic impacts on patient profiles …

Background Acute heart failure (AHF) is a common presentation to the emergency
department (ED), with the potential to cause significant morbidity and mortality. It is important …

Orthostatic hypotension is defined as the reduction of systolic blood pressure of at least 20
mmHg or the dropping of diastolic blood pressure of at least 10 mmHg within 3 minutes of …

Perindopril is a long-acting, once-daily lipophilic angiotensin-converting enzyme inhibitor
with high tissue angiotensin-converting enzyme affinity, lowering angiotensin II and …

Congestive heart failure is characterized by suppressed cardiac output and arterial filling
pressure, leading to renal retention of salt and water, contributing to further volume overload …

Perindopril (Coversyl®) is a prodrug ester of perindoprilat, an ACE inhibitor. This agent has
shown pharmacodynamic effects beyond those responsible for lowering blood pressure …

Ongoing developments in our understanding of cardiovascular disease, together with the
introduction of new drugs to treat these conditions, has led to much debate over the optimal …