Hospital-associated MRSA and antibiotic resistance—what have we learned from genomics?

JA Lindsay - International Journal of Medical Microbiology, 2013 - Elsevier
In many parts of the world, MRSA are responsible for a high proportion of S. aureus
infections in patients in contact with healthcare. Molecular studies have shown this is due to …

Modelling the impact of antibiotic use and infection control practices on the incidence of hospital-acquired methicillin-resistant Staphylococcus aureus: a time-series …

MA Aldeyab, DL Monnet… - Journal of …, 2008 - academic.oup.com
Abstract Objectives Methicillin-resistant Staphylococcus aureus (MRSA) is a major
nosocomial pathogen worldwide. A wide range of factors have been suggested to influence …

The effect of antibiotics on methicillin-resistant Staphylococcus aureus

SJ Dancer - Journal of Antimicrobial Chemotherapy, 2008 - academic.oup.com
Antimicrobial drugs encourage the overgrowth of organisms resistant to the agents used.
Acquisition and subsequent overgrowth of methicillin-resistant Staphylococcus aureus …

Architecture of a species: phylogenomics of Staphylococcus aureus

PJ Planet, A Narechania, L Chen, B Mathema… - Trends in …, 2017 - cell.com
A deluge of whole-genome sequencing has begun to give insights into the patterns and
processes of microbial evolution, but genome sequences have accrued in a haphazard …

Temporal effects of antibiotic use and hand rub consumption on the incidence of MRSA and Clostridium difficile

N Vernaz, H Sax, D Pittet, P Bonnabry… - Journal of …, 2008 - academic.oup.com
Objectives The aim of this study was to determine the temporal relation between the use of
antibiotics and alcohol-based hand rubs (ABHRs) and the incidence of methicillin-resistant …

Antimicrobial stewardship—the state of the art in 2011 focus on outcome and methods

JE McGowan - Infection Control & Hospital Epidemiology, 2012 - cambridge.org
Antimicrobial stewardship programs attempt to optimize prescribing of these drugs to benefit
both current and future patients. Recent regulatory and other incentives have led to …

Perils of quinolone exposure in cancer patients: breakthrough bacteremia with multidrug‐resistant organisms

G Rangaraj, BP Granwehr, Y Jiang… - … Journal of the …, 2010 - Wiley Online Library
BACKGROUND: The objective of this study was to determine the effect of antibiotic use
(including prophylaxis) on the emergence of multidrug‐resistant (MDR) breakthrough …

Relationship between rates of antimicrobial consumption and the incidence of antimicrobial resistance in Staphylococcus aureus and Pseudomonas aeruginosa …

AM Rogues, C Dumartin, B Amadéo… - Infection Control & …, 2007 - cambridge.org
Objective. To investigate relationships between rates of antimicrobial consumption and the
incidence of antimicrobial resistance in Staphylococcus aureus and Pseudomonas …

Cefpodoxime vs ciprofloxacin for short-course treatment of acute uncomplicated cystitis: a randomized trial

TM Hooton, PL Roberts, AE Stapleton - Jama, 2012 - jamanetwork.com
Context Although fluoroquinolones remain the most reliable urinary antimicrobial, resistance
rates have increased and effective fluoroquinolone-sparing antimicrobials are needed …

Role of antimicrobial restrictions in bacterial resistance control: a systematic literature review

M Chatzopoulou, L Reynolds - Journal of Hospital Infection, 2020 - Elsevier
Background Antimicrobial stewardship is considered as one of the most fundamental
aspects of bacterial resistance control. Among the multitude of initiatives, restrictive …