[HTML][HTML] The multifaceted nature of IL-10: regulation, role in immunological homeostasis and its relevance to cancer, COVID-19 and post-COVID conditions

V Carlini, DM Noonan, E Abdalalem, D Goletti… - Frontiers in …, 2023 - frontiersin.org
Interleukin-10 (IL-10) is a pleiotropic cytokine that has a fundamental role in modulating
inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory …

An overview on the treatments and prevention against COVID-19

Y Panahi, AM Gorabi, S Talaei, F Beiraghdar… - Virology Journal, 2023 - Springer
Background The coronavirus disease 2019 (COVID-19) caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to plague the world. While …

Risk of autoimmune diseases following COVID-19 and the potential protective effect from vaccination: a population-based cohort study

K Peng, X Li, D Yang, SCW Chan, J Zhou… - …, 2023 - thelancet.com
Background Case reports suggest that SARS-CoV-2 infection could lead to immune
dysregulation and trigger autoimmunity while COVID-19 vaccination is effective against …

Prospective roles of tumor necrosis factor-alpha (TNF-α) in COVID-19: prognosis, therapeutic and management

Z Mohd Zawawi, J Kalyanasundram… - International journal of …, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) became a worldwide concern at the beginning of
2020 and has affected millions. Several previous studies revealed the impact of the …

Nucleocapsid-specific T cell responses associate with control of SARS-CoV-2 in the upper airways before seroconversion

TM Eser, O Baranov, M Huth, MIM Ahmed… - Nature …, 2023 - nature.com
Despite intensive research since the emergence of SARS-CoV-2, it has remained unclear
precisely which components of the early immune response protect against the development …

Endotheliopathy in acute COVID-19 and long COVID

AG Vassiliou, CS Vrettou, C Keskinidou… - International Journal of …, 2023 - mdpi.com
The pulmonary endothelium is a highly regulated organ that performs a wide range of
functions under physiological and pathological conditions. Since endothelial dysfunction …

PCSK9 inhibition during the inflammatory stage of SARS-CoV-2 infection

EP Navarese, P Podhajski, PA Gurbel… - Journal of the American …, 2023 - jacc.org
Background The intensity of inflammation during COVID-19 is related to adverse outcomes.
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is involved in low-density lipoprotein …

The influence of COVID-19 infection-associated immune response on the female reproductive system

M Saadedine, M El Sabeh, MA Borahay… - Biology of …, 2023 - academic.oup.com
Abstract Coronavirus disease 2019 (COVID-19) is a multi-system disease that has led to a
pandemic with unprecedented ramifications. The pandemic has challenged scientists for the …

Laboratory findings and biomarkers in long COVID: what do we know so far? Insights into epidemiology, pathogenesis, therapeutic perspectives and challenges

D Tsilingiris, NG Vallianou, I Karampela… - International Journal of …, 2023 - mdpi.com
Long COVID (LC) encompasses a constellation of long-term symptoms experienced by at
least 10% of people after the initial SARS-CoV-2 infection, and so far it has affected about 65 …

Cerebral small vessel disease pathology in COVID-19 patients: A systematic review

CD Owens, CB Pinto, S Detwiler, P Mukli… - Ageing Research …, 2023 - Elsevier
Cerebral small vessel disease (CSVD) is the leading cause of vascular cognitive impairment
and is associated with COVID-19. However, contributing factors that often accompany CSVD …