Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …

Abstract SARS-CoV-2, the virus responsible for the COVID-19 pandemic, has been
associated with substantial global morbidity and mortality. Despite a tropism that is largely …

RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

Abstract Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and is characterized by a delayed interferon (IFN) response …

SUMMARY Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). The global COVID-19 pandemic continues to …

Abstract Coronaviral methyltransferases (MTases), nsp10/16 and nsp14, catalyze the last
two steps of viral RNA-cap creation that takes place in cytoplasm. This cap is essential for …

Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 has caused millions of
deaths since its emergence in 2019. Innate immune antagonism by lethal CoVs such as …

Stress granules (SGs) are cytoplasmic condensates that often form as part of the cellular
antiviral response. Despite the growing interest in understanding the interplay between SGs …

Coronaviruses generate double-stranded (ds) RNA intermediates during viral replication
that can activate host immune sensors. To evade activation of the host pattern recognition …

Coronaviruses have evolved a wide array of tactics to evade host antiviral immunity. When
host cells detect invading foreign nucleic acids including viral genome and viral replication …