Although myocardial ischaemia usually manifests as a consequence of atherosclerosis-
dependent obstructive epicardial coronary artery disease, a significant percentage of …

Cardioprotection aims at infarct size reduction and improvement of clinical outcome from
myocardial infarction. The translation of cardioprotection from preclinical and promising …

Aims Microvascular obstruction (MVO) is the underlying cause for the no-reflow
phenomenon in ST-segment elevation myocardial infarction (STEMI). The association …

Acute myocardial infarction (MI) is a major cause of death and disability worldwide. In
patients with MI, the treatment of choice for reducing acute myocardial ischemic injury and …

The success of a primary percutaneous intervention (PCI) in the setting of ST elevation
myocardial infarction depends on the functional and structural integrity of coronary …

The discovery of nitric oxide (NO) as a crucial endothe-lium-derived molecule for vascular
relaxation and the recognition of the endothelium as more than a passive interface between …

The coronary circulation is both culprit and victim of acute myocardial infarction. The rupture
of an epicardial atherosclerotic plaque with superimposed thrombosis causes coronary …

Ischaemic heart disease (IHD) remains the leading cause of death and disability in Europe
and worldwide. A major cause of morbidity and mortality in IHD patients is an acute ST …

Background: Although the prognostic value of findings from cardiac magnetic resonance
(CMR) imaging has been established in single-center center studies in patients with ST …

Once myocardium dies during a heart attack, it is replaced by scar tissue over the course of
several weeks. The size, location, composition, structure and mechanical properties of the …