Vitamin D intervenes in calcium and phosphate metabolism and bone homeostasis.
Experimental studies have shown that 1, 25-dihydroxyvitamin D (calcitriol) generates …

Systemic lupus erythematosus (SLE) is a devastating autoimmune disease that can result in
substantial morbidity and mortality. Diagnosis and treatment of SLE are clinical challenges …

Systemic lupus erythematosus (SLE) is a worldwide chronic autoimmune disease which
may affect every organ and tissue. Genetic predisposition, environmental triggers, and the …

Systemic lupus erythematosus (SLE) is an autoimmune disease characterised by the loss of
self-tolerance and formation of nuclear autoantigens and immune complexes resulting in …

Vitamin D plays a key role in in calcium homeostasis and, thus, provides an important
support in bone growth by aiding in the mineralization of the collagen matrix. However …

Vitamin D (VitD) is a prohormone most noted for the regulation of calcium and phosphate
levels in circulation, and thus of bone metabolism. Inflammatory and immune cells not only …

Vitamin D has been reported to influence physiological systems that extend far beyond its
established functions in calcium and bone homeostasis. Prominent amongst these are the …

Over the last three decades, it has become clear that the role of vitamin D goes beyond the
regulation of calcium homeostasis and bone health. An important extraskeletal effect of …

The classical function of Vitamin D, which involves mineral balance and skeletal
maintenance, has been known for many years. With the discovery of vitamin D receptors in …

Hypovitaminosis D in childhood is a re-emerging public health problem in developed
countries. New life style habits, current “epidemics” of obesity in children and adolescents …