Objective The United States is facing an epidemic of opioid addiction. Deaths from opioid
overdose have quadrupled in the past 15 years and now surpass annual deaths during the …

Background: Opioid use, abuse, and adverse consequences, including death, have
escalated at an alarming rate since the 1990s. In an attempt to control opioid abuse …

Abstract Purpose of Review This review summarizes selected recent evidence on issues
important for preoperative pain evaluation. Recent Findings Opioids, though a mainstay of …

Importance Opioids are commonly used for pain control during and after invasive
procedures. However, opioid-related adverse drug events (ORADEs) are common and have …

Background Oliceridine (TRV130), a novel μ-receptor G-protein pathway selective (μ-GPS)
modulator, was designed to improve the therapeutic window of conventional opioids by …

Objective Opioid analgesics are a mainstay for acute pain management, but postoperative
opioid administration has risks. We examined the prevalence, risk factors, and …

Virtual reality (VR) has emerged as a novel and effective non-pharmacologic therapy for
pain, and there is growing interest to use VR in the acute hospital setting. We sought to …

Hospital‐based clinicians frequently treat acute, noncancer pain. Although opioids may be
beneficial in this setting, the benefits must be balanced with the risks of adverse events …

BACKGROUND: The treatment of postsurgical pain with prescription opioids has been
associated with persistent opioid use and increased health care utilization and costs …

Abstract Background and Aims We created a multicomponent intervention to improve pain
management in the immediate postoperative period with the goal of improving the quality of …