[HTML][HTML] Long COVID or post-acute sequelae of COVID-19 (PASC): an overview of biological factors that may contribute to persistent symptoms

AD Proal, MB VanElzakker - Frontiers in microbiology, 2021 - frontiersin.org
The novel virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused
a pandemic of coronavirus disease 2019 (COVID-19). Across the globe, a subset of patients …

Innate immunological pathways in COVID-19 pathogenesis

SR Paludan, TH Mogensen - Science immunology, 2022 - science.org
Coronavirus disease 2019 (COVID-19) is a disease characterized by a profound
dysregulation of the innate immune system. This knowledge has emerged from the large …

Outcomes of patients with HIV and COVID-19 co-infection: a systematic review and meta-analysis

C Danwang, JJ Noubiap, A Robert… - AIDS research and therapy, 2022 - Springer
Background Data on the association of human immunodeficiency virus (HIV) infection with
adverse outcomes in patients with COVID-19 are conflicting. This systematic review and …

The mechanism underlying extrapulmonary complications of the coronavirus disease 2019 and its therapeutic implication

Q Ning, D Wu, X Wang, D Xi, T Chen, G Chen… - Signal transduction and …, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) is a highly transmissible disease
caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that poses a …

The effects of COVID-19 on the placenta during pregnancy

HS Rad, J Röhl, N Stylianou, MC Allenby… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has caused a global pandemic. The virus primarily affects the …

Infection induces tissue-resident memory NK cells that safeguard tissue health

IS Schuster, XYX Sng, CM Lau, DR Powell… - Immunity, 2023 - cell.com
Tissue health is dictated by the capacity to respond to perturbations and then return to
homeostasis. Mechanisms that initiate, maintain, and regulate immune responses in tissues …

Malignancy-associated haemophagocytic lymphohistiocytosis

A Setiadi, A Zoref-Lorenz, CY Lee, MB Jordan… - The Lancet …, 2022 - thelancet.com
Haemophagocytic lymphohistiocytosis (HLH) is an inflammatory syndrome that can occur
with cancer (malignancy-associated HLH) or with immune-activating therapies for cancer …

RBC-hitchhiking chitosan nanoparticles loading methylprednisolone for lung-targeting delivery

Y Ding, B Lv, J Zheng, C Lu, J Liu, Y Lei, M Yang… - Journal of Controlled …, 2022 - Elsevier
Hyper-inflammation associated with cytokine storm syndrome causes high mortality in
patients with COVID-19. Glucocorticoids, such as methylprednisolone sodium succinate …

Validated international definition of the thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly clinical subtype (TAFRO) of …

Y Nishimura, DC Fajgenbaum… - American Journal of …, 2021 - Wiley Online Library
Thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly
(TAFRO) syndrome is a heterogeneous entity manifesting with a constellation of symptoms …

Diabetes, metformin and the clinical course of Covid-19: outcomes, mechanisms and suggestions on the therapeutic use of metformin

CJ Bailey, M Gwilt - Frontiers in pharmacology, 2022 - frontiersin.org
Objectives: Pre-existing or new diabetes confers an adverse prognosis in people with Covid-
19. We reviewed the clinical literature on clinical outcomes in metformin-treated subjects …