Mounting evidence indicates that inflammatory cytokines contribute to the development of
depression in both medically ill and medically healthy individuals. Cytokines are important …

A plethora of research has implicated hundreds of putative biomarkers for depression, but
has not yet fully elucidated their roles in depressive illness or established what is abnormal …

How do adverse childhood experiences get 'under the skin'and influence health outcomes
through the life-course? Research reviewed here suggests that adverse childhood …

Motivational and motor deficits are common in patients with depression and other psychiatric
disorders, and are related to symptoms of anhedonia and motor retardation. These deficits in …

Obesity is a prevalent global-health problem associated with substantial morbidity,
impairment and economic burden. Because most readily available forms of treatment are …

Among people exposed to major psychological stressors in early life, there are elevated
rates of morbidity and mortality from chronic diseases of aging. The most compelling data …

Objectives: Evidence suggests that childhood maltreatment may negatively affect not only
the lifetime risk of depression but also clinically relevant measures of depression, such as …

Early life stress, such as childhood abuse, neglect and loss, is a well established major risk
factor for developing depressive disorders later in life. We here summarize and discuss …

Childhood maltreatment is likely to influence fundamental biological processes and engrave
long-lasting epigenetic marks, leading to adverse health outcomes in adulthood. We aimed …

Background Maternal inflammation during pregnancy increases the risk for offspring
psychiatric disorders and other adverse long-term health outcomes. The influence of …