Allostatic load in children: The cost of empathic concern

DY Phua, H Chen, F Yap, YS Chong… - Proceedings of the …, 2023 - National Acad Sciences
Early-life adversity affects long-term health outcomes but there is considerable
interindividual variability in susceptibility to environmental influences. We proposed that …

The impact of childhood maltreatment on biological systems: Implications for clinical interventions

A Gonzalez - Paediatrics & child health, 2013 - academic.oup.com
Childhood maltreatment represents a significant risk factor for the development of a number
of mental and physical health outcomes. Converging evidence suggests that early adversity …

Psychological stress in children may alter the immune response

E Carlsson, A Frostell, J Ludvigsson… - The journal of …, 2014 - journals.aai.org
Psychological stress is a public health issue even in children and has been associated with
a number of immunological diseases. The aim of this study was to examine the relationship …

[HTML][HTML] Adverse childhood experiences and early life inflammation in the Avon longitudinal study of parents and children

RE Lacey, M Bartley, M Kelly-Irving… - …, 2020 - Elsevier
Abstract Background Adverse childhood experiences (ACEs) have been associated with
poorer health across the life course. Previous studies have used cumulative risk scores …

Recalled maltreatment, migraine, and tension-type headache: results of the AMPP study

GE Tietjen, DC Buse, KM Fanning, D Serrano… - Neurology, 2015 - AAN Enterprises
Objective: To examine the relationship of recalled adverse childhood experiences (ACEs)
with migraine and episodic tension-type headache (ETTH). Methods: We conducted a cross …

Prenatal and childhood adverse life events, inflammation and depressive symptoms across adolescence

E Flouri, M Francesconi, E Midouhas… - Journal of affective …, 2020 - Elsevier
Background No study has investigated the role of inflammation in explaining the association
between early exposures to adverse life events and depressive symptoms in adolescence …

Adverse childhood experiences are associated with migraine and vascular biomarkers

GE Tietjen, J Khubchandani… - … : The Journal of Head …, 2012 - Wiley Online Library
Objectives.—Migraine is a risk factor for stroke in young women. Biomarker studies implicate
endothelial activation as a possible mechanism. Emerging relationships of childhood …

Retrospectively reported childhood physical abuse, systemic inflammation, and resting corticolimbic connectivity in midlife adults

TE Kraynak, AL Marsland, JL Hanson… - Brain, Behavior, and …, 2019 - Elsevier
Childhood abuse confers risk for psychopathology and pathophysiology in midlife through
intermediate pathways that remain unclear. Systemic inflammation was tested in the present …

Pathways between early‐life adversity and adolescent self‐harm: the mediating role of inflammation in the Avon Longitudinal Study of Parents and Children

AE Russell, J Heron, D Gunnell, T Ford… - Journal of child …, 2019 - Wiley Online Library
Background Adverse childhood experiences (ACEs) such as physical and emotional abuse
are strongly associated with self‐harm, but mechanisms underlying this relationship are …

Oxidative dysregulation in early life stress and posttraumatic stress disorder: a comprehensive review

E Karanikas, NP Daskalakis, A Agorastos - Brain Sciences, 2021 - mdpi.com
Traumatic stress may chronically affect master homeostatic systems at the crossroads of
peripheral and central susceptibility pathways and lead to the biological embedment of …