[HTML][HTML] A bidirectional relationship between depression and the autoimmune disorders–New perspectives from the National Child Development Study
Background Depression and the autoimmune disorders are comorbid—the two classes of
disorders overlap in the same individuals at a higher frequency than chance. The immune …
disorders overlap in the same individuals at a higher frequency than chance. The immune …
Social bonds do not mediate the relationship between early adversity and adult glucocorticoids in wild baboons
In humans and other animals, harsh conditions in early life can have profound effects on
adult physiology, including the stress response. This relationship may be mediated by a lack …
adult physiology, including the stress response. This relationship may be mediated by a lack …
[HTML][HTML] Effects of physical activity in child and adolescent depression and anxiety: role of inflammatory cytokines and stress-related peptide hormones
S Hu, X Li, L Yang - Frontiers in Neuroscience, 2023 - frontiersin.org
Depression and anxiety are the most common mental illnesses affecting children and
adolescents, significantly harming their well-being. Research has shown that regular …
adolescents, significantly harming their well-being. Research has shown that regular …
Early life stress, systemic inflammation, and neural correlates of implicit emotion regulation in adolescents
Exposure to early life stress (ELS) increases the risk for developing psychopathology;
however, the mechanisms underlying this association are not clear. In this study we …
however, the mechanisms underlying this association are not clear. In this study we …
[PDF][PDF] Inflammation, reward circuitry and symptoms of anhedonia and PTSD in trauma-exposed women
Trauma exposure is associated with increased inflammatory biomarkers (eg C-reactive
protein [CRP] and cytokines), and inflammation has been shown to impact corticostriatal …
protein [CRP] and cytokines), and inflammation has been shown to impact corticostriatal …
Role of inflammation in depression and treatment implications
JC Felger - Antidepressants: From Biogenic Amines to New …, 2019 - Springer
Approximately one third of depressed patients fail to respond to currently available
antidepressant therapies. Therefore, new conceptual frameworks are needed to identify …
antidepressant therapies. Therefore, new conceptual frameworks are needed to identify …
Antenatal depression and offspring psychopathology: the influence of childhood maltreatment
S Pawlby, D Hay, D Sharp, CS Waters… - The British journal of …, 2011 - cambridge.org
BackgroundAntenatal depression and childhood maltreatment have each been associated
with offspring psychopathology, but have never been examined in the same sample. AimsTo …
with offspring psychopathology, but have never been examined in the same sample. AimsTo …
[HTML][HTML] Adverse childhood experiences and adult inflammation: Findings from the 1958 British birth cohort
M Chen, RE Lacey - Brain, behavior, and immunity, 2018 - Elsevier
Background The relationship between adverse childhood experiences (ACE) and poorer
health across the life course is well established. Increased chronic inflammation might be …
health across the life course is well established. Increased chronic inflammation might be …
[HTML][HTML] The pediatric buccal epigenetic clock identifies significant ageing acceleration in children with internalizing disorder and maltreatment exposure
F Dammering, J Martins, K Dittrich, D Czamara… - Neurobiology of …, 2021 - Elsevier
Background Studies reporting accelerated ageing in children with affective disorders or
maltreatment exposure have relied on algorithms for estimating epigenetic age derived from …
maltreatment exposure have relied on algorithms for estimating epigenetic age derived from …
Future directions in the study of early-life stress and physical and emotional health: implications of the neuroimmune network hypothesis
Early-life stress is associated with increased vulnerability to physical and emotional health
problems across the lifespan. The recently developed neuroimmune network hypothesis …
problems across the lifespan. The recently developed neuroimmune network hypothesis …