While trait positive emotionality and state positive-valence affect have long been the subject
of intense study, the importance of differentiating among several “discrete” positive emotions …

Objective: Our objective was to update the guidelines for the evaluation and treatment of
androgen deficiency syndromes in adult men published previously in 2006. Participants …

Purpose: The purpose of this guideline is to provide a clinical strategy for the diagnosis and
treatment of erectile dysfunction. Materials and Methods: A systematic review of the literature …

Purpose: There has been a marked increase in testosterone prescriptions in the past
decade resulting in a growing need to give practicing clinicians proper guidance on the …

Objective: To formulate clinical practice guidelines for hormonal replacement in
hypopituitarism in adults. Participants: The participants include an Endocrine Society …

Importance Rates of testosterone therapy are increasing and the effects of testosterone
therapy on cardiovascular outcomes and mortality are unknown. A recent randomized …

In the GRADE approach, randomized trials start as high-quality evidence and observational
studies as low-quality evidence, but both can be rated down if most of the relevant evidence …

Purpose To provide the evidence-based recommendations on the role of testosterone (T) on
age-related symptoms and signs remains. Methods The Italian Society of Andrology and …

Background Testosterone therapy is increasingly promoted. No randomized placebo-
controlled trial has been implemented to assess the effect of testosterone therapy on …

Objective: The aim was to formulate practice guidelines for endocrine treatment
oftranssexual persons. Evidence: This evidence-based guideline was developed using the …