Background The real-world experience of dupilumab in Chinese is limited, and the initial
loading dose has not yet been deeply explored in patients aged< 6 years. Objective To …

Background Fecal microbiota transplantation (FMT) is an effective treatment for intestinal
and extra-intestinal disorders. Nonetheless, long-term safety and efficacy remain major …

The anti-inflammatory role of extra-adrenal glucocorticoid (GC) synthesis at epithelial
barriers is of increasing interest with regard to the search for alternatives to synthetic …

Abstract Interleukin-33 (IL-33) and its receptor Serum Stimulation-2 (ST2, also called Il1rl1)
are members of the IL-1 superfamily that plays a crucial role in allergic diseases. The …

Background: N-3 polyunsaturated fatty acids (PUFAs) have anti-inflammatory properties and
are expected to prevent the onset of allergies. However, epidemiological studies …

Background: The reduction of pharmacological treatment after allergen immunotherapy (AIT)
for house dust mites (HDMs) has been little studied in children. Objective: To evaluate the …

Food allergies (FA), a major public health problem recognized by the World Health
Organization, affect an estimated 3%–10% of adults and 8% of children worldwide …

Allergic diseases, which are closely related to the composition and metabolism of maternal
and infant flora, are prevalent in infants worldwide. The mother's breast milk, intestinal, and …

Objective Allergic rhinitis (AR) and asthma are becoming one of the most prevalent diseases
in children. Identifying sensitization to aeroallergens is seemed to be valuable for …

Background Atopic dermatitis (AD) is the most common chronic inflammatory skin disease in
both pediatric and adult populations. The development of AD has been linked to antibiotic …