Hyperinflammatory response in COVID-19: a systematic review

MJA Silva, LR Ribeiro, MIM Gouveia, BR Marcelino… - Viruses, 2023 - mdpi.com
COVID-19 is a multisystemic disease caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). The immunopathogenic conditions of the hyperinflammatory …

Molecular mechanisms of COVID-19-induced pulmonary fibrosis and epithelial-mesenchymal transition

P Pi, Z Zeng, L Zeng, B Han, X Bai, S Xu - Frontiers in Pharmacology, 2023 - frontiersin.org
As the outbreak of COVID-19 caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) first broke out in Hubei Province, China, at the end of 2019. It has brought …

SARS-CoV-2 spike glycoprotein S1 induces neuroinflammation in BV-2 microglia

OA Olajide, VU Iwuanyanwu, OD Adegbola… - Molecular …, 2022 - Springer
In addition to respiratory complications produced by SARS‐CoV‐2, accumulating evidence
suggests that some neurological symptoms are associated with the disease caused by this …

Induction of exaggerated cytokine production in human peripheral blood mononuclear cells by a recombinant SARS-CoV-2 spike glycoprotein S1 and its inhibition by …

OA Olajide, VU Iwuanyanwu, I Lepiarz-Raba… - Inflammation, 2021 - Springer
An understanding of the pathological inflammatory mechanisms involved in SARS-CoV-2
virus infection is necessary in order to discover new molecular pharmacological targets for …

Bioactive Components of Houttuynia cordata Thunb and Their Potential Mechanisms Against COVID-19 Using Network Pharmacology and Molecular Docking …

H Yuan, L Liu, J Zhou, T Zhang, JW Daily… - Journal of medicinal …, 2022 - liebertpub.com
We investigated the molecular mechanism by which Houttuynia cordata Thunb (HCT) may
intervene in coronavirus disease 2019 (COVID-19) and COVID-19-induced cytokine storms …

Kaempferol has potential anti‐coronavirus disease 2019 (COVID‐19) targets based on bioinformatics analyses and pharmacological effects on endotoxin‐induced …

Y Sun, Q Tao, Y Cao, T Yang, L Zhang… - Phytotherapy …, 2023 - Wiley Online Library
COVID‐19 has infected 272 million patients and caused 5.33 million deaths around the
world, and it remains the main global threat. Previous studies revealed that Chinese …

The impact understanding of exosome therapy in COVID-19 and preparations for the future approaches in dealing with infectious diseases and inflammation

Z Nasiri, H Soleimanjahi, N Baheiraei, SM Hashemi… - Scientific Reports, 2024 - nature.com
Cytokine storms, which result from an abrupt, acute surge in the circulating levels of different
pro-inflammatory cytokines, are one of the complications associated with severe acute …

The effects of high dose vitamin D supplementation as a nutritional intervention strategy on biochemical and inflammatory factors in adults with COVID-19: Study …

Z Khorasanchi, A Jafazadeh Esfehani… - Nutrition and …, 2022 - journals.sagepub.com
Introduction: Low serum vitamin D has been shown to be a risk factor for Coronavirus 2019
(COVID-19). The aim of this study was to assess the effects of high dose vitamin D …

Association of COVID-19 transmission with high levels of ambient pollutants: Initiation and impact of the inflammatory response on cardiopulmonary disease

A Lai, ML Chang, RP O'Donnell, C Zhou… - Science of the Total …, 2021 - Elsevier
Ambient air pollution contributes to 7 million premature deaths annually. Concurrently, the
ongoing coronavirus disease 2019 (COVID-19) pandemic, complicated with S-protein …

Pathological features and neuroinflammatory mechanisms of SARS-CoV-2 in the brain and potential therapeutic approaches

A Sodagar, R Javed, H Tahir, SIA Razak, M Shakir… - Biomolecules, 2022 - mdpi.com
The number of deaths has been increased due to COVID-19 infections and uncertain
neurological complications associated with the central nervous system. Post-infections and …