Understanding neutralization is particularly relevant to an appreciation of the interaction
between a virus and its antibody-synthesizing host since it is likely that viruses and the …

Antisera were raised against peptide sequences that are normally internal in the poliovirus
virion. These antisera contain neutralizing activity, but this neutralizing activity is dependent …

Poliovirus capsid protein undergoes pH-dependent reversible conformational transitions
between state A (isoelectric point about 7) and state B (isoelectric point about 4.5). When …

Adsorption of neutralized poliovirus to HeLa cells was studied using purified virus labeled
with either 32 P (an RNA label) or 14 C (a protein label). The effect of three variables on the …

Possibly the earliest published expectation and demonstration of the neutralizing capacity of
humoral antibody is contained in the report of Sternberg (1892). He suspected that the blood …

The neutralization of Newcastle disease virus follows first-order kinetics with a reaction rate
dependent upon time, antibody concentration, and temperature. A small fraction of the virus …

The mechanism of the antibody-potentiating action of complement was investigated. In the
neutralization of herpes virus by immune serum, formation of virus-antibody complexes …

The purpose of this chapter is to present an integrated view of the various serological
techniques that have been used in virology. The accent will be placed on the principles that …

Two hundred forty pyridazinamine derivatives were tested for the ability to stabilize the
antigenicity and infectivity of oral poliovirus vaccine subjected to 45 degrees C for 2 h …

This paper continues the important observations of the author on the properties of poliovirus-
neutralizing antibody [see also this Bulletin, 1964, v. 39, 1389]. The dissociation of virus …