Ketogenic diet for human diseases: the underlying mechanisms and potential for clinical implementations

H Zhu, D Bi, Y Zhang, C Kong, J Du, X Wu… - Signal transduction and …, 2022 - nature.com
The ketogenic diet (KD) is a high-fat, adequate-protein, and very-low-carbohydrate diet
regimen that mimics the metabolism of the fasting state to induce the production of ketone …

[HTML][HTML] Effects of ketogenic diet on neuroinflammation in neurodegenerative diseases

Z Jiang, X Yin, M Wang, T Chen, Y Wang, Z Gao… - Aging and …, 2022 - ncbi.nlm.nih.gov
The ketogenic diet (KD) is a low-carbohydrate, high-fat and adequate-protein diet. As a diet
mimicking fasting, it triggers the production of ketone bodies (KBs) and brings the body into …

Ketogenic diet ameliorates cognitive impairment and neuroinflammation in a mouse model of Alzheimer's disease

Y Xu, C Jiang, J Wu, P Liu, X Deng… - CNS Neuroscience …, 2022 - Wiley Online Library
Introduction Alzheimer's disease (AD) is the most common neurodegenerative disorder that
causes dementia and affects millions of people worldwide. Although it has devastating …

Therapeutic strategies to ameliorate neuronal damage in epilepsy by regulating oxidative stress, mitochondrial dysfunction, and neuroinflammation

S Madireddy, S Madireddy - Brain sciences, 2023 - mdpi.com
Epilepsy is a central nervous system disorder involving spontaneous and recurring seizures
that affects 50 million individuals globally. Because approximately one-third of patients with …

Popular dietary trends' impact on athletic performance: a critical analysis review

M Kaufman, C Nguyen, M Shetty, M Oppezzo… - Nutrients, 2023 - mdpi.com
Background: Nutrition fuels optimal performance for athletes. With increased research
developments, numerous diets available, and publicity from professional athletes, a review …

The influence of ketogenic diet on gut Microbiota: potential benefits, risks and indications

A Santangelo, A Corsello, GCI Spolidoro, CM Trovato… - Nutrients, 2023 - mdpi.com
The ketogenic diet (KD) restricts carbohydrate consumption, leading to an increase in
ketone bodies, such as acetoacetate, β-hydroxybutyrate, and acetone, which are utilized as …

On the nutritional and therapeutic effects of ketone body d-β-hydroxybutyrate

A Yao, Z Li, J Lyu, L Yu, S Wei, L Xue, H Wang… - Applied microbiology …, 2021 - Springer
Abstract d-β-hydroxybutyrate (d-3HB), a monomer of microbial polyhydroxybutyrate (PHB), is
also a natural ketone body produced during carbohydrate deprivation to provide energy to …

The metabolic role of ketogenic diets in treating epilepsy

K Imdad, T Abualait, A Kanwal, ZT AlGhannam… - Nutrients, 2022 - mdpi.com
Epilepsy is a long-term neurological condition that results in recurrent seizures.
Approximately 30% of patients with epilepsy have drug-resistant epilepsy (DRE). The …

[HTML][HTML] The role of ketogenic metabolic therapy on the brain in serious mental illness: a review

S Sethi, JM Ford - Journal of psychiatry and brain science, 2022 - ncbi.nlm.nih.gov
In search of interventions targeting brain dysfunction and underlying cognitive impairment in
schizophrenia, we look at the brain and beyond to the potential role of dysfunctional …

Role of ketogenic diet in neurodegenerative diseases focusing on Alzheimer diseases: The guardian angle

HM Al-Kuraishy, MS Jabir, AK Albuhadily… - Ageing Research …, 2024 - Elsevier
The ketogenic diet (KD) is a low-carbohydrate, adequate protein and high-fat diet. KD is
primarily used to treat refractory epilepsy. KD was shown to be effective in treating different …