A brief overview of global trends in MSC-based cell therapy

D Jovic, Y Yu, D Wang, K Wang, H Li, F Xu… - Stem cell reviews and …, 2022 - Springer
Human mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells or
medicinal signaling cells, are important adult stem cells for regenerative medicine, largely …

[HTML][HTML] Engineered mesenchymal stem cell-derived extracellular vesicles: a state-of-the-art multifunctional weapon against Alzheimer's disease

T Yin, Y Liu, W Ji, J Zhuang, X Chen, B Gong, J Chu… - Theranostics, 2023 - ncbi.nlm.nih.gov
With the increase of population aging, the number of Alzheimer's disease (AD) patients is
also increasing. According to current estimates, approximately 11% of people over 65 suffer …

Treatment of Alzheimer's disease: beyond symptomatic therapies

FR Buccellato, M D'Anca, GM Tartaglia… - International Journal of …, 2023 - mdpi.com
In an ever-increasing aged world, Alzheimer's disease (AD) represents the first cause of
dementia and one of the first chronic diseases in elderly people. With 55 million people …

Biomarker and therapeutic potential of peripheral extracellular vesicles in Alzheimer's disease

C Vandendriessche, D Kapogiannis… - Advanced drug delivery …, 2022 - Elsevier
Extracellular vesicles (EVs) are cell-derived nanoparticles with an important role in
intercellular communication, even across brain barriers. The bidirectional brain-barrier …

Comprehensive bibliometric analysis of stem cell research in Alzheimer's disease from 2004 to 2022

R Wang, Y Zhu, LF Qin, ZG Xu, XR Gao… - Dementia and Geriatric …, 2023 - karger.com
Introduction: Stem cell-based regenerative medicine has provided an excellent opportunity
to investigate therapeutic strategies and innovative treatments for Alzheimer's disease (AD) …

The role of neuroinflammation in neurodegenerative diseases: current understanding and future therapeutic targets

A Adamu, S Li, F Gao, G Xue - Frontiers in Aging Neuroscience, 2024 - frontiersin.org
Neuroinflammation refers to a highly complicated reaction of the central nervous system
(CNS) to certain stimuli such as trauma, infection, and neurodegenerative diseases. This is a …

Therapeutic efficacy and promise of stem cell-derived extracellular vesicles in Alzheimer's disease and other aging-related disorders

HA Rather, S Almousa, S Craft, G Deep - Ageing Research Reviews, 2023 - Elsevier
The term extracellular vesicles (EVs) refers to a variety of heterogeneous nanovesicles
secreted by almost all cell types, primarily for intercellular communication and maintaining …

Alzheimer's disease: from pathogenesis to mesenchymal stem cell therapy–bridging the missing link

J Hu, X Wang - Frontiers in cellular neuroscience, 2022 - frontiersin.org
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease worldwide. With
the increasing trend of population aging, the estimated number of AD continues to climb …

Mesenchymal Stem Cell (MSC)-Based Drug Delivery into the Brain across the Blood–Brain Barrier

T Tashima - Pharmaceutics, 2024 - mdpi.com
At present, stem cell-based therapies using induced pluripotent stem cells (iPSCs) or
mesenchymal stem cells (MSCs) are being used to explore the potential for regenerative …

Application of mesenchymal stem cells (MSCs) in neurodegenerative disorders: history, findings, and prospective challenges

N Biglari, A Mehdizadeh, MV Mastanabad… - … -Research and Practice, 2023 - Elsevier
Over the past few decades, the application of mesenchymal stem cells has captured the
attention of researchers and practitioners worldwide. These cells can be obtained from …