A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

Mitochondria are known to generate approximately 90% of cellular reactive oxygen species
(ROS). The imbalance between mitochondrial reactive oxygen species (mtROS) production …

Several chemicals, including environmental toxicants and clinically useful drugs, cause
severe cellular damage to different organs of our body through metabolic activation to highly …

Background Ferroptosis is a recently identified iron-dependent form of cell death as a result
of increased reactive oxygen species (ROS) and lipid peroxidation. In this study, we …

Albuminuria is the hallmark of both primary and secondary proteinuric glomerulopathies,
including focal segmental glomerulosclerosis (FSGS), obesity-related nephropathy, and …

Salvia officinalis (Sage) is a plant in the family of Labiatae/Lamiaceae. It is native to Middle
East and Mediterranean areas, but today has been naturalized throughout the world. In folk …

Amplification of oxidative stress is present since the early stages of chronic kidney disease
(CKD), holding a key position in the pathogenesis of renal failure. Induction of renal pro …

Inflammation contributes to many chronic conditions. It is often associated with circulating
pro-inflammatory cytokines and immune cells. GLP-1 levels correlate with disease severity …

Diabetic kidney disease is known as a major cause of chronic kidney disease and end stage
renal disease. Polysulfides, a class of chemical agents with a chain of sulfur atoms, are …

Simple Summary The progressive nature of type 2 diabetes mellitus (T2DM) leads to micro-
and macro-vascular complications, including renal and cardiovascular disease. These …