[HTML][HTML] Gene-gene and gene-environment interaction data for platinum-based chemotherapy in non-small cell lung cancer
LY Wang, JJ Cui, JY Liu, AX Guo, ZY Zhao, YZ Liu… - Scientific data, 2018 - nature.com
Gene-gene (GXG) and gene-environment (GXE) interactions play important roles in
pharmacogenetics study. Simultaneously incorporating multiple single nucleotide …
pharmacogenetics study. Simultaneously incorporating multiple single nucleotide …
[HTML][HTML] Novel genetic variants of SYK and ITGA1 related lymphangiogenesis signaling pathway predict non-small cell lung cancer survival
Although lymphangiogenesis is a vital step in lung cancer metastasis, the association
between lymphangiogenesis and non-small cell lung cancer (NSCLC) survival remains …
between lymphangiogenesis and non-small cell lung cancer (NSCLC) survival remains …
[PDF][PDF] Metformin as a therapeutic tool for resistant hematological malignancies: a literature review
GS Paz, J Fernandes - Chinese Clinical Oncology, 2024 - cdn.amegroups.cn
Metformin as a therapeutic tool for resistant hematological malignancies: a literature review
Page 1 Page 1 of 22 © Chinese Clinical Oncology. All rights reserved. Chin Clin Oncol 2024 …
Page 1 Page 1 of 22 © Chinese Clinical Oncology. All rights reserved. Chin Clin Oncol 2024 …
[HTML][HTML] Effect of XPD and TP53 gene polymorphisms on the risk of platinum-based chemotherapy induced toxicity in Bangladeshi lung cancer patients
Background: Platinum-based drugs, including cisplatin and carboplatin, are the most active
and extensively used agents for treating lung cancer. Genetic polymorphisms of DNA repair …
and extensively used agents for treating lung cancer. Genetic polymorphisms of DNA repair …
[HTML][HTML] Effect of TOP2A and ERCC1 gene polymorphisms on the efficacy and toxicity of cisplatin and etoposide-based chemotherapy in small cell lung cancer …
M Nicoś, A Rolska-Kopińska, P Krawczyk… - Archives of Medical …, 2021 - ncbi.nlm.nih.gov
Results Patients with C/C genotype in rs13695 of the TOP2A gene had significantly lower
risk of neutropenia during chemotherapy than C/T heterozygous patients (p= 0.02, χ²= 5.51 …
risk of neutropenia during chemotherapy than C/T heterozygous patients (p= 0.02, χ²= 5.51 …
[PDF][PDF] 晚期非小细胞肺癌化学治疗的现状与未来
章必成， 朱波 - 医药导报, 2018 - yydbzz.com
近年来, 化学治疗(化疗) 在晚期非小细胞肺癌(NSCLC) 治疗中的基石地位已经受到了严重的
挑战, 疗效已经遭遇瓶颈. 通过化疗与分子靶向药物, 抗血管生成药物或免疫治疗药物的联合应用 …
挑战, 疗效已经遭遇瓶颈. 通过化疗与分子靶向药物, 抗血管生成药物或免疫治疗药物的联合应用 …
[HTML][HTML] Association Between ERCC1 rs3212986 and ERCC2/XPD rs1799793 and OS in Patients With Advanced Esophageal Cancer
E Boldrin, S Malacrida, E Rumiato, G Battaglia… - Frontiers in …, 2019 - frontiersin.org
Esophageal cancer (EC) is a very aggressive tumor, and no reliable prognostic markers
exist especially for resectable advanced neoplasia. The principal aim of this study was to …
exist especially for resectable advanced neoplasia. The principal aim of this study was to …
Polynuclear ruthenium organometallic compounds induce DNA damage in human cells identified by the nucleotide excision repair factor XPC
OG Fast, B Gentry, L Strouth, MB Niece… - Bioscience …, 2019 - portlandpress.com
Ruthenium organometallic compounds represent an attractive avenue in developing
alternatives to platinum-based chemotherapeutic agents. While evidence has been …
alternatives to platinum-based chemotherapeutic agents. While evidence has been …
ERCC1 and ERCC2 genes expression and their SNPs variants identify a favorable signature for SCLC patients treated with platinum-based chemotherapy
E Caliman, S Fancelli, F Scolari, A Pasqui… - 2023 - researchsquare.com
Background: Platinum chemotherapy (CT) remains the backbone of systemic therapy for
patients with small-cell lung cancer (SCLC). The nucleotide excision repair (NER) pathway …
patients with small-cell lung cancer (SCLC). The nucleotide excision repair (NER) pathway …
Association of T2285C polymorphism in PARP1 gene coding region with its expression, activity and NSCLC risk along with prognosis
Y Wang, XB Xia, HZ Tang, JR Cai, XK Shi, HX Ji… - …, 2021 - academic.oup.com
Abstract Poly (ADP-ribose) polymerase-1 (PARP1), a DNA repair gene, is the crucial player
in the maintenance of genome integrity. T2285C polymorphism in coding region of PARP1 …
in the maintenance of genome integrity. T2285C polymorphism in coding region of PARP1 …