Osteoarthritis (OA) is the most common form of arthritis globally and a major cause of pain,
physical disability, and loss of economic productivity, with currently no causal treatment …

Adiponectin, an adipose-derived hormone, plays a pivotal role in glucose regulation and
lipid metabolism, with a decrease in circulating adiponectin levels being linked to insulin …

The fundamental aim of healthcare is to improve overall health of the population by
providing state-of-the-art healthcare for individuals at an affordable cost. The foundation for …

Historically, the rapid degradation and massive gas release from magnesium (Mg) implants
resulted in severe emphysema and mechanical failure. With the advent of new alloys and …

Chronic wounds represent a significant global burden, afflicting millions with debilitating
complications. Despite standard care, impaired healing persists due to factors like persistent …

Introduction The drug discovery and development 'valley of death'remains a challenge for
promising new therapies originating from academic research laboratories. Drug discovery …

One major drawback of preclinical models to test drug-induced liver injury (DILI) is their
inability to predict the interindividual difference of DILI effect in a population. Consequently …

近年来, 随着现代生物技术的成熟, 在国际社会共同推动下, 致力于为患者提供个性化医疗服务的
精准医疗及其相关临床研究取得了显著进展. 为促进精准医疗研究及其发展环境的优化 …

Nanotheranostics, a rapidly advancing field at the intersection of nanotechnology and
theranostics, holds great promise for revolutionizing personalized veterinary medicine. The …

Background: Phase 2 trials bridge a clinical strategy that shows promise in preclinical
studies to late phase trials that confirm its value. However, high failure rates of these trials …