Natural products for the management of castration-resistant prostate cancer: Special focus on nanoparticles based studies

RK Singla, CS Sai, H Chopra, S Behzad… - Frontiers in cell and …, 2021 - frontiersin.org
Prostate cancer is the most common type of cancer among men and the second most
frequent cause of cancer-related mortality around the world. The progression of advanced …

[HTML][HTML] Nanovaccines: an effective therapeutic approach for cancer therapy

S Gurunathan, P Thangaraj, L Wang, Q Cao… - Biomedicine & …, 2024 - Elsevier
Cancer vaccines hold considerable promise for the immunotherapy of solid tumors.
Nanomedicine offers several strategies for enhancing vaccine effectiveness. In particular …

Natural products derived from medicinal plants and microbes might act as a game-changer in breast cancer: A comprehensive review of preclinical and clinical studies

RK Singla, X Wang, R Gundamaraju… - Critical Reviews in …, 2023 - Taylor & Francis
Breast cancer (BC) is the most prevalent neoplasm among women. Genetic and
environmental factors lead to BC development and on this basis, several preventive …

Natural product-based studies for the management of castration-resistant prostate cancer: Computational to clinical studies

RK Singla, P Sharma, AK Dubey… - Frontiers in …, 2021 - frontiersin.org
Background: With prostate cancer being the fifth-greatest cause of cancer mortality in 2020,
there is a dire need to expand the available treatment options. Castration-resistant prostate …

An immunocompetent environment unravels the proto-oncogenic role of miR-22

ML Centomo, M Vitiello, L Poliseno, PP Pandolfi - Cancers, 2022 - mdpi.com
Simple Summary Through their regulatory activity of gene expression, microRNAs have
been heavily implicated in the genesis of cancer. They can act both as promoters …

The role of androgen receptor and microRNA interactions in androgen-dependent diseases

A Bielska, A Skwarska, A Kretowski… - International journal of …, 2022 - mdpi.com
The androgen receptor (AR) is a member of the steroid hormone receptor family of nuclear
transcription factors. It is present in the primary/secondary sexual organs, kidneys, skeletal …

Identification of microRNAs as viable aggressiveness biomarkers for prostate cancer

LJ Martínez-González, V Sánchez-Conde… - Biomedicines, 2021 - mdpi.com
MiRNAs play a relevant role in PC (prostate cancer) by the regulation in the expression of
several pathways' AR (androgen receptor), cellular cycle, apoptosis, MET (mesenchymal …

Multi-omics network characterization reveals novel microRNA biomarkers and mechanisms for diagnosis and subtyping of kidney transplant rejection

Y Lin, L Wang, W Ge, Y Hui, Z Zhou, L Hu… - Journal of Translational …, 2021 - Springer
Background Kidney transplantation is an optimal method for treatment of end-stage kidney
failure. However, kidney transplant rejection (KTR) is commonly observed to have negative …

[HTML][HTML] Identification of key miRNAs in prostate cancer progression based on miRNA-mRNA network construction

G Dal Santo, M Frasca, G Bertoli, I Castiglioni… - Computational and …, 2022 - Elsevier
Prostate cancer (PC) is one of the major male cancers. Differential diagnosis of PC is
indispensable for the individual therapy, ie, Gleason score (GS) that describes the grade of …

The cuproptosis related genes signature predicts the prognosis and correlates with the immune status of clear cell renal cell carcinoma

P Sun, H Xu, K Zhu, M Li, R Han, J Shen, X Xia… - Frontiers in …, 2022 - frontiersin.org
Background: Clear cell renal cell carcinoma (CCRCC) has a high incidence and poor
prognosis. Cuproptosis, an independent pattern of cell death associated with copper, plays …