Simple Summary Glioblastoma multiforme is a brain tumor with a very unfavorable prognosis, where the vast majority of patients do not survive a year after diagnosis. One line …
S Parik, J Fernández-García, F Lodi… - Frontiers in …, 2022 - frontiersin.org
Glioblastoma is a highly lethal grade of astrocytoma with very low median survival. Despite extensive efforts, there is still a lack of alternatives that might improve these prospects. We …
Dysregulation of fatty acid metabolism and de novo lipogenesis is a key driver of several cancer types through highly unsaturated fatty acid (HUFA) signaling precursors such as …
J Korbecki, M Bosiacki, I Gutowska, D Chlubek… - Cancers, 2023 - mdpi.com
Simple Summary This review discusses the synthesis and significance of fatty acids, glycerophospholipids, and triacylglycerol in glioblastoma. The focus is on all enzymes …
JT Brenna, KSD Kothapalli - Current Opinion in Clinical Nutrition & …, 2022 - journals.lww.com
The mixture of fatty acids available to FADS2 in any tissue defines the product mixture available for further synthesis of membrane lipids and signaling molecules and may be …
J Korbecki, D Simińska, D Jeżewski, K Kojder… - Brain Sciences, 2022 - mdpi.com
One line of research on the possible ways of inhibiting the growth of glioblastoma multiforme (GBM), a brain tumor with a very poor prognosis, is the analysis of its metabolism, such as …
D Simińska, J Korbecki, K Kojder, D Jeżewski… - International Journal of …, 2022 - mdpi.com
Glioblastoma multiforme (GBM) is a malignant glioma, difficult to detect and with the lowest survival rates among gliomas. Its greater incidence among men and its higher survival rate …
J Korbecki, K Kojder, D Jeżewski, D Simińska… - Brain Sciences, 2023 - mdpi.com
This study aimed to analyze solute carrier family 27 (SLC27) in glioblastoma tumors. The investigation of these proteins will provide insight into how and to what extent fatty acids are …
L Sun, B Li, B Wang, J Li, J Li - International Journal of General …, 2022 - Taylor & Francis
Purpose Ferroptosis is closely associated with tumors. The purpose of this study was to investigate the correlation between ferroptosis and prognosis of low grade glioma (LGG) via …