There has recently been a growing interest in examining the role of epigenetic modifications,
such as DNA methylation, in the etiology of type 1 diabetes (T1D). This study aimed to …

Abstract Purpose of Review Osteoarthritis is a complex and highly polygenic disease. Over
100 reported osteoarthritis risk variants fall in non-coding regions of the genome, ostensibly …

The general psychopathology factor (GPF) has been proposed as a way to capture variance
shared between psychiatric symptoms. Despite a growing body of evidence showing both …

Bullying among children is ubiquitous and associated with pervasive mental health
problems. However, little is known about the biological pathways that change after exposure …

Background Illumina DNA methylation microarrays enable epigenome-wide analysis vastly
used for the discovery of novel DNA methylation variation in health and disease. However …

We analysed DNA methylation data from 30 datasets comprising 3474 individuals, 19
tissues and 8 ethnicities at CpGs covered by the Illumina450K array. We identified 4143 …

Alcohol misuse is a major public health problem originating from genetic and environmental
risk factors. Alterations in the brain epigenome may orchestrate changes in gene expression …

Up until now, no study has looked specifically at epigenomic landscapes throughout twin
samples, discordant for Anorexia nervosa (AN). Our goal was to find evidence to confirm the …

Background DNA methylation has been shown to be involved in many biological processes,
including X chromosome inactivation in females, paternal genomic imprinting, and others …

Background A gap exists in our mechanistic understanding of how genetic and
environmental risk factors converge at the molecular level to result in the emergence of …