Genome‐wide DNA methylation patterns associated with sleep and mental health in children: a population‐based study

ME Koopman‐Verhoeff, RH Mulder… - Journal of Child …, 2020 - Wiley Online Library
Background DNA methylation (DNAm) has been implicated in the biology of sleep. Yet, how
DNAm patterns across the genome relate to different sleep outcomes, and whether these …

Epigenetic profiling of social communication trajectories and co-occurring mental health problems: a prospective, methylome-wide association study

J Rijlaarsdam, CAM Cecil, CL Relton… - Development and …, 2022 - cambridge.org
While previous studies suggest that both genetic and environmental factors play an
important role in the development of autism-related traits, little is known about potential …

Epigenetics and hot spots of crime: Rethinking the relationship between genetics and criminal behavior

R Leshem, D Weisburd - Journal of contemporary criminal …, 2019 - journals.sagepub.com
There is a growing recognition of the importance of micro-geographic areas in the
generation of crime problems. While many studies show that crime is heavily concentrated at …

DNA methylation at birth and fine motor ability in childhood: an epigenome-wide association study with replication

F Serdarevic, M Luo, I Karabegović, AC Binter… - Epigenetics, 2023 - Taylor & Francis
Lower fine motor performance in childhood has been associated with poorer cognitive
development and neurodevelopmental conditions such as autism spectrum disorder, yet …

Identification of influential probe types in epigenetic predictions of human traits: implications for microarray design

RF Hillary, DL McCartney, AF McRae, A Campbell… - Clinical …, 2022 - Springer
Background CpG methylation levels can help to explain inter-individual differences in
phenotypic traits. Few studies have explored whether identifying probe subsets based on …

Persistent DNA Methylation Changes across the First Year of Life and Prenatal Exposure in a Canadian Prospective Birth Study

S Lee, H Sbihi, JL MacIsaac, R Balshaw… - Environmental …, 2024 - ehp.niehs.nih.gov
Background: Evidence suggests that prenatal air pollution exposure alters DNA methylation
(DNAm), which could go on to affect long-term health. It remains unclear whether DNAm …

Integrated genetic and methylomic analyses identify shared biology between autism and autistic traits

A Massrali, H Brunel, E Hannon, C Wong… - Molecular autism, 2019 - Springer
Previous studies have identified differences in DNA methylation in autistic individuals
compared to neurotypical individuals. Yet, it is unclear if this extends to autistic traits …

DNA methylation and resting brain function mediate the association between childhood urbanicity and better speed of processing

W Cheng, N Luo, Y Zhang, X Zhang, H Tan… - Cerebral …, 2021 - academic.oup.com
Urbanicity has been suggested to affect cognition, but the underlying mechanism remains
unknown. We examined whether epigenetic modification (DNA methylation, DNAm), and …

Co-methylation analyses identify CpGs associated with lipid traits in Chinese discordant monozygotic twins

Z Li, W Wang, W Li, H Duan, C Xu, X Tian… - Human Molecular …, 2024 - academic.oup.com
To control genetic background and early life milieu in genome-wide DNA methylation
analysis for blood lipids, we recruited Chinese discordant monozygotic twins to explore the …

Running in the FAMILY: understanding and predicting the intergenerational transmission of mental illness

LAEM van Houtum, WFC Baaré, CF Beckmann… - European Child & …, 2024 - Springer
Over 50% of children with a parent with severe mental illness will develop mental illness by
early adulthood. However, intergenerational transmission of risk for mental illness in one's …