Dietary flavonoids: Cardioprotective potential with antioxidant effects and their pharmacokinetic, toxicological and therapeutic concerns

J Khan, PK Deb, S Priya, KD Medina, R Devi… - Molecules, 2021 - mdpi.com
Flavonoids comprise a large group of structurally diverse polyphenolic compounds of plant
origin and are abundantly found in human diet such as fruits, vegetables, grains, tea, dairy …

Systematic review of the common pathophysiological mechanisms in COVID-19 and neurodegeneration: the role of bioactive compounds and natural antioxidants

K Choe, HY Park, M Ikram, HJ Lee, TJ Park, R Ullah… - Cells, 2022 - mdpi.com
The novel coronavirus (2019-nCoVCOVID-19) belongs to the Beta coronavirus family, which
contains MERS-CoV (Middle East respiratory syndrome coronavirus) and SARS-CoV …

Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2

S Sun, H Gu, L Cao, Q Chen, Q Ye, G Yang… - Nature …, 2021 - nature.com
There is an urgent need for animal models to study SARS-CoV-2 pathogenicity. Here, we
generate and characterize a novel mouse-adapted SARS-CoV-2 strain, MASCp36, that …

[HTML][HTML] Repurposing of phytomedicine-derived bioactive compounds with promising anti-SARS-CoV-2 potential: Molecular docking, MD simulation and drug-likeness …

M Rudrapal, N Gogoi, D Chetia, J Khan… - Saudi journal of …, 2022 - Elsevier
In view of the potential of traditional plant-based remedies (or phytomedicines) in the
management of COVID-19, the present investigation was aimed at finding novel anti-SARS …

[HTML][HTML] A comprehensive genomic study, mutation screening, phylogenetic and statistical analysis of SARS-CoV-2 and its variant omicron among different countries

SU Ahmad, BH Kiani, M Abrar, Z Jan, I Zafar… - Journal of Infection and …, 2022 - Elsevier
Background With the rapid development of the genomic sequence data for the Severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants Delta (B. 1.617. 2) and …

[HTML][HTML] Phytocompounds as potential inhibitors of SARS-CoV-2 Mpro and PLpro through computational studies

M Rudrapal, I Celik, S Chinnam, MA Ansari… - Saudi journal of …, 2022 - Elsevier
The inhibition of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main
protease (Mpro) and papain-like protease (PLpro) prevents viral multiplications; these viral …

Comparative assessment of filtration-and precipitation-based methods for the concentration of SARS-CoV-2 and other viruses from wastewater

K Farkas, C Pellett, N Alex-Sanders… - Microbiology …, 2022 - Am Soc Microbiol
Wastewater-based epidemiology (WBE) has been widely used to track levels of SARS-CoV-
2 infection in the community during the COVID-19 pandemic. Due to the rapid expansion of …

A scalable and highly immunogenic virus‐like particle‐based vaccine against SARS‐CoV‐2

MO Mohsen, I Balke, S Zinkhan, V Zeltina, X Liu… - Allergy, 2022 - Wiley Online Library
Background SARS‐CoV‐2 caused one of the most devastating pandemics in the recent
history of mankind. Due to various countermeasures, including lock‐downs, wearing masks …

合成生物学在新冠病毒广谱疫苗研发中的应用

袁为锋, 赵永亮, 吴芷萱, 徐可 - 合成生物学, 2024 - synbioj.cip.com.cn
新型冠状病毒(SARS-CoV-2) 自2019 年底引发疫情至今, 已经变异出Alpha, Beta, Delta
和Omicron 等不同谱系. 传统疫苗的抗原序列来源于某一自然分离株的原始序列 …

Middle East Respiratory Syndrome coronavirus vaccine development: updating clinical studies using platform technologies

J Choi, JO Kim - Journal of Microbiology, 2022 - Springer
Abstract Middle East Respiratory Syndrome coronavirus (MERS-CoV), a contagious
zoonotic virus, causes severe respiratory infection with a case fatality rate of approximately …