For the longest time, the field of nucleic acid delivery has remained skeptical whether or not
polycationic drug carrier systems would ever make it into clinical practice. Yet, with the …

In the last decade, point accumulation for imaging in nanoscale topography (PAINT) has
emerged as a versatile tool for single-molecule localization microscopy (SMLM). Currently …

Therapeutic nucleic acids are an emerging class of therapy for treating various diseases
through immunomodulation, protein replacement, gene editing, and genetic engineering …

Oligopeptide end–modified poly (β-amino ester) s (OM-pBAEs) offer a means for the
effective implementation of gene therapeutics in the near future. A fine-tuning of OM-pBAEs …

Nanoparticles (NPs) are used to encapsulate therapeutic cargos and deliver them
specifically to the target site. The intracellular trafficking of NPs dictates the NP-cargo …

Nanoparticle‐mediated intracellular delivery of oligonucleotides is a complex phenomenon
that depends on the architecture and the intracellular trafficking of the engineered …

The increasing number of approved nucleic acid therapeutics demonstrates the potential for
the prevention and treatment of a broad spectrum of diseases. This trend underscores the …

Gene therapy is being used in many applications, including pest control and the treatment of
diseases. However, protection during transport and delivery of the genetic material to the …

Nanomedicine is a field at the intersection of nanotechnology and medicine, promising due
to its potential to revolutionize healthcare. Despite its long trajectory, there is still a long road …

Immunotherapy has emerged as a promising approach to cancer treatment, offering
improved survival rates and enhanced patients' quality of life. However, realizing the full …