Immune function and micronutrient requirements change over the life course

S Maggini, A Pierre, PC Calder - Nutrients, 2018 - mdpi.com
As humans age, the risk and severity of infections vary in line with immune competence
according to how the immune system develops, matures, and declines. Several factors …

Vitamin D supplementation, serum 25 (OH) D concentrations and cardiovascular disease risk factors: a systematic review and meta-analysis

N Mirhosseini, J Rainsbury, SM Kimball - Frontiers in cardiovascular …, 2018 - frontiersin.org
Background: Cardiovascular disease (CVD) risk factors are associated with low serum 25
hydroxyvitamin D (25 (OH) D) concentrations in observational studies; however, clinical trial …

Does serum vitamin D level affect COVID-19 infection and its severity?-A case-control study

K Ye, F Tang, X Liao, BA Shaw, M Deng… - Journal of the …, 2021 - Taylor & Francis
Background As effective medication to treat COVID-19 is currently unavailable, preventive
remedies may be particularly important. Objective To examine the relationship between …

Impact of vitamin D deficiency on COVID-19—a prospective analysis from the CovILD Registry

A Pizzini, M Aichner, S Sahanic, A Böhm, A Egger… - Nutrients, 2020 - mdpi.com
The novel Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus type 2 (SARS-CoV-2) is a global health concern. Vitamin D (VITD) …

Gut microbiota interactions with the immunomodulatory role of vitamin D in normal individuals

RV Luthold, GR Fernandes, AC Franco-de-Moraes… - Metabolism, 2017 - Elsevier
Background Due to immunomodulatory properties, vitamin D status has been implicated in
several diseases beyond the skeletal disorders. There is evidence that its deficiency …

[HTML][HTML] Vitamin D: A master example of nutrigenomics

C Carlberg, M Raczyk, N Zawrotna - Redox Biology, 2023 - Elsevier
Nutrigenomics attempts to characterize and integrate the relation between dietary molecules
and gene expression on a genome-wide level. One of the biologically active nutritional …

Vitamin D and autoimmune rheumatic diseases

L Athanassiou, I Kostoglou-Athanassiou, M Koutsilieris… - Biomolecules, 2023 - mdpi.com
Vitamin D is a steroid hormone with potent immune-modulating properties. It has been
shown to stimulate innate immunity and induce immune tolerance. Extensive research …

Mechanisms of action of vitamin D in colon cancer

G Ferrer-Mayorga, MJ Larriba, P Crespo… - The Journal of steroid …, 2019 - Elsevier
Colorectal cancer (CRC) is the neoplasia that is most frequently associated with vitamin D
deficiency in epidemiological and observational studies in terms of incidence and mortality …

Role of vitamin D in the hygiene hypothesis: the interplay between vitamin D, vitamin D receptors, gut microbiota, and immune response

A Clark, N Mach - Frontiers in immunology, 2016 - frontiersin.org
The hygiene hypothesis postulates that higher levels of cleanliness and improper exposure
to microorganisms early in childhood could disturb the intestinal microbiome resulting in …

PFAPA syndrome: a review on treatment and outcome

F Vanoni, K Theodoropoulou, M Hofer - Pediatric Rheumatology, 2016 - Springer
The syndrome of periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis
(PFAPA syndrome) is the most common cause of periodic fever in childhood. The current …