The traditional two-dimensional (2D) in vitro cell culture system (on a flat support) has long
been used in cancer research. However, this system cannot be fully translated into clinical …

Three‐dimensional cell culture models, such as spheroids, can be used in the process of the
development of new anticancer agents because they are able to closely mimic the main …

In vitro drug screening is widely used in the development of new drugs, because they
constitute a cost-effective approach to select compounds with more potential for therapy …

Many extracellular matrices (ECMs) have a filamentous architecture, which influences cell
growth and phenotype and imparts tissues with specific properties. Man-made fibrillar …

Three-dimensional multicellular tumor models are receiving an ever-growing focus as
preclinical drug-screening platforms due to their potential to recapitulate major physiological …

Despite advances in breast cancer diagnosis and treatment, many patients still fail therapy,
resulting in disease progression, recurrence, and reduced overall survival. Historically …

In the 21st century, chemotherapy stands as a primary treatment method for prevalent
diseases, yet drug resistance remains a pressing challenge. Utilizing electrospinning to …

Electrospinning is historically related to tissue engineering due to its ability to produce nano-
/microscale fibrous materials with mechanical and functional properties that are extremely …

Collagen is the most abundant component of the extracellular matrix (ECM), therefore it
represents an ideal biomaterial for the culture of a variety of cell types. Recently, collagen …

Although antibiotic is still the main choice for antibacteria both in hospital and community,
phototherapy has become a possibly one of the alternative approaches in the treatment of …