Understanding COVID-19-associated coagulopathy

EM Conway, N Mackman, RQ Warren… - Nature Reviews …, 2022 - nature.com
Abstract COVID-19-associated coagulopathy (CAC) is a life-threatening complication of
SARS-CoV-2 infection. However, the underlying cellular and molecular mechanisms driving …

Respiratory sequelae of COVID-19: pulmonary and extrapulmonary origins, and approaches to clinical care and rehabilitation

SJ Singh, MM Baldwin, E Daynes, RA Evans… - The Lancet …, 2023 - thelancet.com
Although the exact prevalence of post-COVID-19 condition (also known as long COVID) is
unknown, more than a third of patients with COVID-19 develop symptoms that persist for …

Impact of COVID-19 on the liver and on the care of patients with chronic liver disease, hepatobiliary cancer, and liver transplantation: An updated EASL position paper

T Marjot, CS Eberhardt, T Boettler, LS Belli… - Journal of …, 2022 - Elsevier
The COVID-19 pandemic has presented a serious challenge to the hepatology community,
particularly healthcare professionals and patients. While the rapid development of safe and …

The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …

DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications

DB Kell, GJ Laubscher, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Post-acute sequelae of COVID (PASC), usually referred to as 'Long COVID'(a phenotype of
COVID-19), is a relatively frequent consequence of SARS-CoV-2 infection, in which …

[HTML][HTML] Good practice statements for antithrombotic therapy in the management of COVID‐19: guidance from the SSC of the ISTH

AC Spyropoulos, JM Connors, JD Douketis… - Journal of Thrombosis …, 2022 - Elsevier
Despite the emergence of high quality randomized trial data with the use of antithrombotic
agents to reduce the risk of thromboembolism, end‐organ failure, and possibly mortality in …

Exosomal miR-145 and miR-885 regulate thrombosis in COVID-19

J Gambardella, U Kansakar, C Sardu, V Messina… - … of Pharmacology and …, 2023 - ASPET
We hypothesized that exosomal microRNAs could be implied in the pathogenesis of
thromboembolic complications in coronavirus disease 2019 (COVID-19). We isolated …

NLRP3 inflammasome and interleukin-1 contributions to COVID-19-associated coagulopathy and immunothrombosis

N Potere, E Garrad, Y Kanthi, M Di Nisio… - Cardiovascular …, 2023 - academic.oup.com
Immunothrombosis—immune-mediated activation of coagulation—is protective against
pathogens, but excessive immunothrombosis can result in pathological thrombosis and …

Clinical update on COVID-19 for the emergency and critical care clinician: Medical management

B Long, S Chavez, BM Carius, WJ Brady… - The American Journal of …, 2022 - Elsevier
Introduction Coronavirus disease of 2019 (COVID-19) has resulted in millions of cases
worldwide. As the pandemic has progressed, the understanding of this disease has evolved …

COVID-19 outcomes in persons with hemophilia: results from a US-based national COVID-19 surveillance registry

A Sharathkumar, L Wendt, C Ortman… - Journal of thrombosis …, 2024 - Elsevier
Background Hypercoagulable state contributing to thrombotic complications worsens COVID-
19 severity and outcomes, whereas anticoagulation improves outcomes by alleviating …