Enhancing regenerative medicine: the crucial role of stem cell therapy

J Wang, G Deng, S Wang, S Li, P Song, K Lin… - Frontiers in …, 2024 - frontiersin.org
Stem cells offer new therapeutic avenues for the repair and replacement of damaged tissues
and organs owing to their self-renewal and multipotent differentiation capabilities. In this …

Cellular modifications and biomaterial design to improve mesenchymal stem cell transplantation

JKU Wong, A Mehta, TT Vũ, GC Yeo - Biomaterials Science, 2023 - pubs.rsc.org
Research has advanced considerably since the first clinical trial of human mesenchymal
stem cells (MSCs) in the early 1990s. During this period, our understanding of MSC biology …

Effect and safety of mesenchymal stem cells for patients with COVID‐19: Systematic review and meta‐analysis with trial sequential analysis

Z Zhang, S Shao, X Liu, Z Tong - Journal of Medical Virology, 2023 - Wiley Online Library
The objective of this study was to assess whether mesenchymal stem cells (MSCs) therapy
could offer survival advantages for patients with novel coronavirus disease 2019 (COVID …

Mesenchymal stromal cell therapy in lung transplantation

AI Nykänen, M Liu, S Keshavjee - Bioengineering, 2023 - mdpi.com
Lung transplantation is often the only viable treatment option for a patient with end-stage
lung disease. Lung transplant results have improved substantially over time, but ischemia …

Exosomes as a nano-carrier for Chemotherapeutics: a new era of oncology

RP Araldi, DA Delvalle, VR da Costa, AL Alievi… - Cells, 2023 - mdpi.com
Despite the considerable advancements in oncology, cancer remains one of the leading
causes of death worldwide. Drug resistance mechanisms acquired by cancer cells and …

The Plastic Interplay between Lung Regeneration Phenomena and Fibrotic Evolution: Current Challenges and Novel Therapeutic Perspectives

S Lettieri, FR Bertuccio, L Del Frate, F Perrotta… - International Journal of …, 2023 - mdpi.com
Interstitial lung diseases (ILDs) are a heterogeneous group of pulmonary disorders
characterized by variable degrees of inflammation, interstitial thickening, and fibrosis …

Manufacturing, quality control, and GLP-grade preclinical study of nebulized allogenic adipose mesenchymal stromal cells-derived extracellular vesicles

J Wang, Z Chen, Z Zhang, M Shen, B Zhao… - Stem Cell Research & …, 2024 - Springer
Background Human adipose stromal cells-derived extracellular vesicles (haMSC-EVs) have
been shown to alleviate inflammation in acute lung injury (ALI) animal models. However …

[HTML][HTML] Adipose tissue-derived mesenchymal stromal cells attenuate acute lung injury induced by trauma and haemorrhagic shock

Z Zhang, X Yang, Q Meng, Y Long, X Shi, Y Wang - Immunobiology, 2023 - Elsevier
Abstract Background Mesenchymal stromal cells (MSCs) have shown promising therapeutic
options for acute lung injury (ALI) caused by multiple factors. Here, we evaluated the …

MesenchymAl stromal cells for Traumatic bRain Injury (MATRIx): a study protocol for a multicenter, double-blind, randomised, placebo-controlled phase II trial

ER Zanier, F Pischiutta, E Rulli, A Vargiolu… - Intensive Care Medicine …, 2023 - Springer
Background Traumatic brain injury (TBI) is a significant cause of death and disability, with no
effective neuroprotective drugs currently available for its treatment. Mesenchymal stromal …

Review of current and potential applications of mesenchymal stem cells in exotic animal species

VA Johnson - Journal of the American Veterinary Medical …, 2024 - Am Vet Med Assoc
The discovery that a population of cells derived from adult tissues had regenerative
properties and could be expanded and utilized therapeutically led to an abundance of …