Hepatocellular carcinoma is today the sixth leading cause of cancer-related death
worldwide, despite the decreased incidence of chronic hepatitis infections. This is due to the …

Simple Summary Increasing evidence indicates that cancer stem cells (CSCs) are the main
factor responsible for therapeutic resistance and tumor relapse in primary liver cancer (PLC) …

Hepatocellular carcinoma (HCC) is a liver cancer, highly heterogeneous both at the
histopathological and molecular levels. It arises from hepatocytes as the result of the …

High‐coverage mass spectrometry analysis of single‐cell metabolomics remains
challenging due to the extremely low abundance and wide polarity of metabolites and ultra …

Even though colon cancer ranks among the leading causes of cancer mortality, early
detection dramatically increases survival rates. Many studies have been conducted to …

Exosomal miRNAs (exo-miRNAs) have arisen as novel diagnostic biomarkers for various
cancers. However, few reports on exo-miRNAs related to bone metastasis (BM) in lung …

Background Graphene materials have the capacity to influence the tumor microenvironment
and intracellular signaling responsiveness. However, the process of graphene-assisted liver …

Recently, studies on the mechanisms underlying lipid metabolic reprogramming in cancer
have increased. However, its significance in cervical cancer remains unclear. In the present …

Background Acute ischemic stroke (AIS) is one of the leading contributors to death and
disability in adults. And cuproptosis is a novel type of cell death. Yet, its role in AIS is still …

糖酵解是原发性肝癌代谢重编程过程中重要的生物学事件, 其机制主要受糖酵解途径中的关键限
速酶, 包括已糖激酶(hexokinase, HK), 丙酮酸激酶(pyruvate kinase, PK), 磷酸果糖激酶 …