The orbitofrontal cortex in primates including humans is the key brain area in emotion, and
in the representation of reward value and in non-reward, that is not obtaining an expected …

The orbitofrontal cortex represents the reward or affective value of primary reinforcers
including taste, touch, texture, and face expression. It learns to associate other stimuli with …

Finding robust brain substrates of mood disorders is an important target for research. The
degree to which major depression (MDD) and bipolar disorder (BD) are associated with …

The past decade has seen a transformation in research on the retrosplenial cortex (RSC).
This cortical area has emerged as a key member of a core network of brain regions that …

This review begins with a brief historical overview of attempts in the first half of the 20th
century to discern brain systems that underlie emotion and emotional behavior. These early …

The neural networks that putatively modulate aspects of normal emotional behavior have
been implicated in the pathophysiology of mood disorders by converging evidence from …

The ability to regulate emotions is an important part of adaptive functioning in society.
Advances in cognitive and affective neuroscience and biological psychiatry have facilitated …

The anterior cingulate cortex (ACC) ventral to the genu of the corpus callosum has been
implicated in the modulation of emotional behavior on the basis of neuroimaging studies in …

Unlike neurologic conditions, such as brain tumors, dementia, and stroke, the neural
mechanisms for all psychiatric disorders remain unclear. A large body of research obtained …

BACKGROUND: Recent genetic results have indicated that the two major, classically distinct
forms of psychosis–schizophrenia and bipolar disorder–may share causative factors in …