Long-term cardiovascular consequences of fetal growth restriction: biology, clinical implications, and opportunities for prevention of adult disease

F Crispi, J Miranda, E Gratacós - American journal of obstetrics and …, 2018 - Elsevier
In the modern world, cardiovascular disease is a leading cause of death for both men and
women. Epidemiologic studies consistently have suggested an association between low …

Mechanisms of fetal adaptation to chronic hypoxia following placental insufficiency: a review

R Ramirez Zegarra, A Dall'Asta, T Ghi - Fetal Diagnosis and Therapy, 2022 - karger.com
Placental insufficiency is associated with reduced oxygen and nutrient supply to the fetus,
which may result in fetal growth restriction (FGR). In an attempt to cope with the hostile …

Fetal cardiovascular remodeling persists at 6 months in infants with intrauterine growth restriction

M Cruz‐Lemini, F Crispi… - … in Obstetrics & …, 2016 - Wiley Online Library
Objectives Intrauterine growth restriction is associated with increased cardiovascular risk
later in life but the link between fetal disease and postnatal risk is not well‐documented. We …

Fetal cardiac function in late‐onset intrauterine growth restriction vs small‐for‐gestational age, as defined by estimated fetal weight, cerebroplacental ratio and uterine …

M Pérez‐Cruz, M Cruz‐Lemini… - … in Obstetrics & …, 2015 - Wiley Online Library
Objective Among late‐onset small fetuses, a combination of estimated fetal weight (EFW),
cerebroplacental ratio (CPR) and mean uterine artery (UtA) pulsatility index (PI) can predict …

Perinatal changes in cardiac geometry and function in growth‐restricted fetuses at term

O Patey, JS Carvalho… - Ultrasound in Obstetrics …, 2019 - Wiley Online Library
Objective To evaluate the effect of fetal growth restriction (FGR) at term on fetal and neonatal
cardiac geometry and function. Methods This was a prospective study of 87 pregnant …

A fetal cardiovascular score to predict infant hypertension and arterial remodeling in intrauterine growth restriction

M Cruz-Lemini, F Crispi, B Valenzuela-Alcaraz… - American journal of …, 2014 - Elsevier
Objective Intrauterine growth restricted (IUGR) fetuses experience cardiovascular
remodeling that persists into infancy and has been related to cardiovascular outcomes in …

Assessment of fetal cardiac morphology and functional changes in early‐onset and late‐onset fetal growth restriction

D Oluklu, D Menekse Beser… - … of Gynecology & …, 2023 - Wiley Online Library
Objective To compare the fetal cardiac morphology and functions of early‐onset fetal growth
restriction (EO‐FGR) and late‐onset fetal growth restriction (LO‐FGR) groups with …

Longitudinal annular systolic displacement compared to global strain in normal fetal hearts and those with cardiac abnormalities

GR DeVore, B Klas, G Satou… - Journal of Ultrasound in …, 2018 - Wiley Online Library
Objectives The purpose of this study was to compare a new technique that measures the
midventricular basal‐apical longitudinal diastolic and systolic lengths, computes the …

Maternal obesity affects fetal myocardial function as early as in the first trimester

CB Ingul, L Lorås, E Tegnander… - … in Obstetrics & …, 2016 - Wiley Online Library
Objective To investigate cardiac function from 14 weeks' gestation in fetuses of obese
pregnant women (FOW). Animal studies have shown that maternal obesity induces fibrosis …

Ultrasound assessment of fetal cardiac function

F Crispi, B Valenzuela‐Alcaraz… - … journal of ultrasound …, 2013 - Wiley Online Library
Introduction: Fetal heart evaluation with US is feasible and reproducible, although
challenging due to the smallness of the heart, the high heart rate and limited access to the …