Epigenetics in health and disease

L Zhang, Q Lu, C Chang - Epigenetics in allergy and autoimmunity, 2020 - Springer
Epigenetic mechanisms, which include DNA methylation, histone modification, and
microRNA (miRNA), can produce heritable phenotypic changes without a change in DNA …

The therapeutic potential and role of miRNA, lncRNA, and circRNA in osteoarthritis

Y Wu, X Lu, B Shen, Y Zeng - Current gene therapy, 2019 - ingentaconnect.com
Background: Osteoarthritis (OA) is a disease characterized by progressive degeneration,
joint hyperplasia, narrowing of joint spaces, and extracellular matrix metabolism. Recent …

[HTML][HTML] Targeting the NLRP3 inflammasome as new therapeutic avenue for inflammatory bowel disease

QL Chen, HR Yin, QY He, Y Wang - Biomedicine & Pharmacotherapy, 2021 - Elsevier
The incidence and prevalence of inflammatory bowel disease (IBD) are increasing
worldwide. Current approved medication for IBD treatment in the clinic mainly includes …

Anti‐Inflammatory Effect of Clostridium butyricum‐Derived Extracellular Vesicles in Ulcerative Colitis: Impact on Host microRNAs Expressions and Gut Microbiome …

L Ma, W Lyu, Y Song, K Chen, L Lv… - Molecular Nutrition & …, 2023 - Wiley Online Library
Score Probiotics extracellular vesicles (EVs) have shown potential as EV‐based
nanomaterials therapy for the treatment of inflammatory bowel disease (IBD). Although …

MicroRNAs in inflammatory bowel disease and its complications

SS Krishnachaitanya, M Liu, K Fujise, Q Li - International journal of …, 2022 - mdpi.com
Inflammatory bowel disease (IBD), classified primarily between Crohn's disease and
ulcerative colitis, is a collection of chronic gastrointestinal inflammatory conditions that cause …

[HTML][HTML] Roles of microRNAs in inflammatory bowel disease

HT Jung, JS Kim, KH Lee, K Tizaoui… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal
tract that mainly affects young people. IBD is associated with various gastrointestinal …

Probiotics and MicroRNA: their roles in the host–microbe interactions

Y Zhao, Y Zeng, D Zeng, H Wang, M Zhou… - Frontiers in …, 2021 - frontiersin.org
Probiotics are widely accepted to be beneficial for the maintenance of the gut homeostasis–
the dynamic and healthy interactions between host and gut microorganisms. In addition …

The increase of miR-195-5p reduces intestinal permeability in ulcerative colitis, modulating tight junctions' expression

V Scalavino, E Piccinno, G Bianco, N Schena… - International Journal of …, 2022 - mdpi.com
Defects in the intestinal epithelial barrier functions characterize inflammatory conditions
such as Inflammatory Bowel Disease (IBD). Overexpression of pro-inflammatory cytokines …

Serum miRNAs are pharmacodynamic biomarkers associated with therapeutic response in pediatric inflammatory bowel disease

SK Batra, CR Heier, L Diaz-Calderon… - Inflammatory Bowel …, 2020 - academic.oup.com
Background We sought to identify microRNAs (miRNAs) associated with response to anti-
TNF-α or glucocorticoids in children with inflammatory bowel disease (IBD) to generate …

The role of autophagy and related microRNAs in inflammatory bowel disease

S Wang, Y Huang, C Zhou, H Wu… - Gastroenterology …, 2018 - Wiley Online Library
Accumulating evidence demonstrates that microRNA‐(miR‐) mediated posttranscriptional
regulation plays an important role in autophagy in inflammatory bowel disease (IBD), a …