The role of cytokines and chemokines in severe acute respiratory syndrome coronavirus 2 infections

RJ Hsu, WC Yu, GR Peng, CH Ye, SY Hu… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …

Immunogenicity of COVID-19 vaccines in patients with diabetes mellitus: A systematic review

AB Boroumand, M Forouhi, F Karimi… - Frontiers in …, 2022 - frontiersin.org
Purpose To evaluate the immunogenicity of COVID-19 vaccines in patients with diabetes
mellitus (DM) through a systematic approach. Method A comprehensive search was …

Azvudine is a thymus-homing anti-SARS-CoV-2 drug effective in treating COVID-19 patients

JL Zhang, YH Li, LL Wang, HQ Liu, SY Lu… - Signal transduction and …, 2021 - nature.com
Azvudine (FNC) is a nucleoside analog that inhibits HIV-1 RNA-dependent RNA polymerase
(RdRp). Recently, we discovered FNC an agent against SARS-CoV-2, and have taken it into …

Does poor glycaemic control affect the immunogenicity of the COVID‐19 vaccination in patients with type 2 diabetes: the CAVEAT study

R Marfella, N D'Onofrio, C Sardu… - Diabetes, Obesity …, 2022 - Wiley Online Library
1 BACKGROUND Type 2 diabetes (T2D) is associated with an increased risk of infection-
related morbidity and mortality. 1 Accordingly, coronavirus disease 2019 (COVID-19) results …

[HTML][HTML] Viral proteases as therapeutic targets

T Majerová, J Konvalinka - Molecular aspects of medicine, 2022 - Elsevier
Some medically important viruses―including retroviruses, flaviviruses, coronaviruses, and
herpesviruses―code for a protease, which is indispensable for viral maturation and …

Modulation of macrophage polarization by viruses: turning off/on host antiviral responses

S Yu, H Ge, S Li, HJ Qiu - Frontiers in microbiology, 2022 - frontiersin.org
Macrophages are professional antigen-presenting cells and serve as the first line of defense
against invading pathogens. Macrophages are polarized toward the proinflammatory …

Immune response to COVID-19 during pregnancy

G Chen, Q Liao, J Ai, B Yang, H Bai, J Chen… - Frontiers in …, 2021 - frontiersin.org
Pregnant women are generally more susceptible to viral infection. Although the impact of
SARS-CoV-2 on pregnant women remains to be determined, evidence indicates that risks of …

Procalcitonin for individualizing antibiotic treatment: an update with a focus on COVID-19

S Wolfisberg, C Gregoriano… - Critical reviews in clinical …, 2022 - Taylor & Francis
Procalcitonin (PCT) is useful for differentiating between viral and bacterial infections and for
reducing the unnecessary use of antibiotics. As the rise of antimicrobial resistance reaches …

Spontaneous cancer remission after COVID-19: insights from the pandemic and their relevance for cancer treatment

C Meo, G Palma, F Bruzzese, A Budillon… - Journal of Translational …, 2023 - Springer
Early in the COVID-19 pandemic, it emerged that the risk of severe outcomes was greater in
patients with co-morbidities, including cancer. The huge effort undertaken to fight the …

Monocytic HLA-DR expression in immune responses of acute pancreatitis and COVID-19

S Liu, W Luo, P Szatmary, X Zhang, JW Lin… - International Journal of …, 2023 - mdpi.com
Acute pancreatitis is a common gastrointestinal disease with increasing incidence
worldwide. COVID-19 is a potentially life-threatening contagious disease spread throughout …