Beyond transferring genetic information, RNAs are molecules with diverse functions that
include catalyzing biochemical reactions and regulating gene expression. Most of these …

Abstract mRNA medicine is a new and rapidly developing field in which the delivery of
genetic information in the form of mRNA is used to direct therapeutic protein production in …

RNA methylation at adenosine N6 (m6A) is one of the most common RNA modifications,
impacting RNA stability, transport, and translation. Previous studies uncovered RNA …

Epitranscriptomic modification of RNA regulates human development, health, and disease.
The true diversity of the transcriptome in breast cancer including chemical modification of …

Conformational dynamics is crucial for ribonucleic acid (RNA) function. Techniques such as
nuclear magnetic resonance, cryo-electron microscopy, small-and wide-angle X-ray …

Nearest neighbor parameters for estimating the folding stability of RNA secondary structures
are in widespread use. For helices, current parameters penalize terminal AU base pairs …

Performing alchemical transformations, in which one molecular system is nonphysically
changed to another system, is a popular approach adopted in performing free energy …

RNA molecules carry out various cellular functions, and understanding the mechanisms
behind their functions requires the knowledge of their 3D structures. Different types of …

RNA performs various spatiotemporal functions in living cells. As the solution environments
significantly affect the stability of RNA duplexes, a stability prediction of the RNA duplexes in …

RNA viruses are diverse and abundant pathogens that are responsible for numerous human
diseases. RNA viruses possess relatively compact genomes and have therefore evolved …