Acute respiratory distress syndrome in COVID-19: possible mechanisms and therapeutic management

A Aslan, C Aslan, NM Zolbanin, R Jafari - Pneumonia, 2021 - Springer
COVID-19 pandemic is a serious concern in the new era. Acute respiratory distress
syndrome (ARDS), and lung failure are the main lung diseases in COVID-19 patients. Even …

Drug safety of frequently used drugs and substances for self-medication in COVID-19

D Baracaldo-Santamaría… - … advances in drug …, 2022 - journals.sagepub.com
During the COVID-19 pandemic, the behavior of self-medication has increased. The
dissemination of misleading information regarding the efficacy of certain drugs or …

The complexity of SARS-CoV-2 infection and the COVID-19 pandemic

MK da Silva Torres, CDA Bichara… - Frontiers in …, 2022 - frontiersin.org
The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) led to the death of millions of people worldwide and thousands more infected individuals …

Efficacy and safety of hydroxychloroquine as pre-and post-exposure prophylaxis and treatment of COVID-19: A systematic review and meta-analysis of blinded …

PR Martins-Filho, LC Ferreira, L Heimfarth… - The Lancet Regional …, 2021 - thelancet.com
Background Hydroxychloroquine (HCQ) is an anti-malarial and immunomodulatory drug
considered a potential candidate for drug repurposing in COVID-19 due to their in vitro …

Drug repurposing against SARS-CoV-1, SARS-CoV-2 and MERS-CoV

S Aherfi, B Pradines, C Devaux, S Honore… - Future …, 2021 - Taylor & Francis
Since the beginning of the COVID-19 pandemic, large in silico screening studies and
numerous in vitro studies have assessed the antiviral activity of various drugs on SARS-CoV …

Tenofovir, another inexpensive, well-known and widely available old drug repurposed for SARS-COV-2 infection

I Zanella, D Zizioli, F Castelli, E Quiros-Roldan - Pharmaceuticals, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is spreading
worldwide with different clinical manifestations. Age and comorbidities may explain severity …

Pregnancy and COVID-19: high or low risk of vertical transmission

HM Al-Kuraishy, AI Al-Gareeb, NKA Albezrah… - Clinical and …, 2023 - Springer
Abstract Coronavirus disease 19 (COVID-19) is an infectious disease caused by severe
acute respiratory syndrome 2 (SARS-CoV-2). Throughout the pandemic, evidence on the …

The failure of drug repurposing for COVID-19 as an effect of excessive hypothesis testing and weak mechanistic evidence

M Maziarz, A Stencel - History and Philosophy of the Life Sciences, 2022 - Springer
The current strategy of searching for an effective treatment for COVID-19 relies mainly on
repurposing existing therapies developed to target other diseases. Conflicting results have …

SARS-CoV-2 treatment: current therapeutic options and the pursuit of tailored therapy

G Marciano, R Roberti, C Palleria, D Mirra, V Rania… - Applied Sciences, 2021 - mdpi.com
One year on from the worldwide outbreak of severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2), medicine has made several steps towards increasing the therapeutic …

Current potential therapeutic approaches against SARS-CoV-2: a review

DK Yadav, DD Singh, I Han, Y Kumar, EH Choi - Biomedicines, 2021 - mdpi.com
The ongoing SARS-CoV-2 pandemic is a serious threat to public health worldwide and, to
date, no effective treatment is available. Thus, we herein review the pharmaceutical …