Molecular machinery regulating exocytosis

T Shandala, R Kakavanos-Plew, YS Ng… - … and Integration of …, 2012 - books.google.com
Exocytosis is the major intracellular route for the delivery of proteins and lipids to the plasma
membrane and the means by which vesicular contents are released into the extracellular …

Trastuzumab emtansine (T-DM1) for the treatment of HER2-positive cancer with a focus on breast cancer

HS Rugo, IE Krop, YW Chu - Antibody-Drug Conjugates and …, 2012 - Springer
Overexpression of human epidermal growth factor receptor type 2 (HER2; neu; ErbB2) is an
important histopathologic feature in a variety of human solid tumors. HER2 is a member of …

[引用][C] Exo70 intracellular redistribution after repeated mild traumatic brain injury

MS Lira Mendieta, P Zamorano, WF Cerpa Nebott - 2021

A conserved role for Syntaxin-1 in pre-and post-commissural midline axonal guidance in fly, chick, and mouse

O Ros i Torres, PJ Barrecheguren Manero… - PLoS Genetics, 2018 …, 2018 - diposit.ub.edu
Axonal growth and guidance rely on correct growth cone responses to guidance cues.
Unlike the signaling cascades that link axonal growth to cytoskeletal dynamics, little is …

Development of a novel in vitro model system to characterize the role of activity in motor neurons during development and disease

E Aubrey - 2017 - dalspace.library.dal.ca
Neural activity modulates motor axon guidance and synaptic function during development.
Differences in neural activity also contribute to the demise of specific motor neuron subtypes …

Adhesion Molecules in Synapse Assembly and Function

P Chipman, Y Goda - Dendrites: Development and Disease, 2016 - Springer
As the nervous system develops, cell adhesion molecules (CAMs) interact across the
synaptic junction to govern synapse assembly and function. The CAM interactions are highly …

Regulation of patterned dynamics of local exocytosis in growth cones by netrin-1

O Ros i Torres, T Cotrufo… - … of Neuroscience, 2015 …, 2015 - diposit.ub.edu
Axonal guidance and synaptic specification depends on specific signaling mechanisms that
occur in growth cones. While several signaling pathways implicated in cone navigation have …

Identification of novel cytosolic binding partners of the neural cell adhesion molecule NCAM and functional analysis of these interactions

HJ Wobst - 2014 - bonndoc.ulb.uni-bonn.de
The neural cell adhesion molecule (NCAM) plays an important role during brain
development and in adult brain. NCAM functions through interactions with several proteins …

[PDF][PDF] Intracellular signaling and driving mechanisms underlying neuronal growth cone guidance

糸總るり香, イトフサルリカ - 2015 - toyaku.repo.nii.ac.jp
During embryonic nervous system development, individual neurons extend axons, long and
thin processes that connect to distant cells, to establish precise neuronal networks. The …

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M Fais, G Sanna, M Galioto, TTD Nguyen, NT Tr - J. Biol. Chem, 2014 - academia.edu
Mutations in LRRK2 play a critical role in both familial and sporadic Parkinson's disease
(PD). Up to date, the role of LRRK2 in PD onset and progression remains largely unknown …