[HTML][HTML] Therapeutic implications of current Janus kinase inhibitors as anti-COVID agents: A review

NK Jain, M Tailang, HK Jain… - Frontiers in …, 2023 - frontiersin.org
Severe cases of COVID-19 are characterized by hyperinflammation induced by cytokine
storm, ARDS leading to multiorgan failure and death. JAK-STAT signaling has been …

[HTML][HTML] Prospects of novel and repurposed immunomodulatory drugs against acute respiratory distress syndrome (ARDS) associated with covid-19 disease

SS Nayak, A Naidu, SL Sudhakaran, S Vino… - Journal of personalized …, 2023 - mdpi.com
Acute respiratory distress syndrome (ARDS) is intricately linked with SARS-CoV-2-
associated disease severity and mortality, especially in patients with co-morbidities. Lung …

[HTML][HTML] Interaction of Laurusides 1 and 2 with the 3C-like Protease (Mpro) from Wild-Type and Omicron Variant of SARS-CoV-2: A Molecular Dynamics Study

I Autiero, GN Roviello - International Journal of Molecular Sciences, 2023 - mdpi.com
Laurus nobilis (bay laurel) is a natural source of biological compounds, and some of its
extracts and phytocompounds are also endowed with antiviral activity toward the family of …

[HTML][HTML] Search of inhibitors of aldose reductase for treatment of diabetic cataracts using machine learning

T Chen, R Chen, A You, VL Kouznetsova… - … Practice and Research, 2023 - Elsevier
Purpose Patients with diabetes mellitus have an elevated chance of developing cataracts, a
degenerative vision-impairing condition often needing surgery. The process of the reduction …

Pharmacotherapeutics for cytokine storm in COVID-19

R Pal, MJ Chaudhary - Stem Cells, 2024 - Elsevier
Cytokine storm (CS) is an acute hyperinflammatory response that may be responsible for
critical illness in many conditions, including viral infections, cancer, sepsis (bacterial), and …