The genus Ebolavirus from the family Filoviridae is composed of five species including
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …

The Marburg virus (MV), identified in 1967, has caused deadly outbreaks worldwide, the
mortality rate of Marburg virus disease (MVD) varies depending on the outbreak and virus …

Filoviruses, including Ebola virus, pose an increasing threat to the public health. Although
two therapeutic monoclonal antibodies have been approved to treat the Ebola virus …

Marburg virus (MARV) is a highly pathogenic virus associated with severe disease and
mortality rates as high as 90%. Outbreaks of MARV are sporadic, deadly, and often …

Monoclonal antibodies (mAbs) and remdesivir, a small-molecule antiviral, are promising
monotherapies for many viruses, including members of the genera Marburgvirus and …

A major challenge in managing acute viral infections is ameliorating disease when treatment
is delayed. Previously, we reported the success of a 2-pronged mAb and antiviral remdesivir …

Emerging infectious diseases of zoonotic origin are an ever-increasing public health risk
and economic burden. The factors that determine if and when an animal virus is able to spill …

Obeldesivir (ODV, GS-5245) is an orally administered prodrug of the parent nucleoside of
remdesivir (RDV) and is presently in phase 3 trials for COVID-19 treatment. In this work, we …

Background The recent outbreaks of Marburg virus disease (MVD) in Guinea and Ghana
have become a major public health concern not only to the West African sub-region but a …

Objective To describe and quantify the extent of wildlife and environment sector inclusion in
country evaluation and prioritization tools for health security, and to provide practical …