W Jia, L Zhou, L Li, P Zhou, Z Shen - Pharmaceuticals, 2023 - mdpi.com
Polyphenols and their derivates, a kind of natural product distributed in herb plants, vegetables, and fruits, are the most abundant antioxidants in the human diet and have been …
FM Hanson, RE Hodgson, MIR de Oliveira… - Bioscience …, 2022 - portlandpress.com
Eukaryotic initiation factor 2B, eIF2B is a guanine nucleotide exchange, factor with a central role in coordinating the initiation of translation. During stress and disease, the activity of …
A Rubio, GD Garland, A Sfakianos, RF Harvey… - Seminars in Cancer …, 2022 - Elsevier
In tumourigenesis, oncogenes or dysregulated tumour suppressor genes alter the canonical translation machinery leading to a reprogramming of the translatome that, in turn, promotes …
CL Lines, MJ McGrath, T Dorwart, CS Conn - Frontiers in Oncology, 2023 - frontiersin.org
During their quest for growth, adaptation, and survival, cancer cells create a favorable environment through the manipulation of normal cellular mechanisms. They increase …
E Varone, A Decio, MC Barbera, M Bolis… - British Journal of …, 2022 - Wiley Online Library
Background and Purpose Endoplasmic reticulum (ER) stress triggers an adaptive response in tumours which fosters cell survival and resilience to stress. Activation of the ER stress …
T Wai - Trends in Endocrinology & Metabolism, 2024 - cell.com
Mitochondria are double membrane-bound organelles the network morphology of which in cells is shaped by opposing events of fusion and fission executed by dynamin-like GTPases …
G Ma, Z Zhao, Y Qu, F Cai, S Liu, H Liang… - Cell Death …, 2022 - nature.com
Abstract Whereas cysteine dioxygenase 1 (CDO1) expression is lost due to its hypermethylated promoter across a range of cancer types including gastric cancer (GC), its …
RX Chen, SD Xu, MH Deng, SH Hao… - … and Targeted Therapy, 2024 - nature.com
Abstract RNA-binding proteins (RBPs)-RNA networks have contributed to cancer development. Circular RNAs (circRNAs) are considered as protein recruiters; nevertheless …
D Li, T Chen, QG Li - BMC Pulmonary Medicine, 2023 - Springer
Background Both N6-methyladenosine (m6A) and ferroptosis-related genes are associated with the prognosis of lung adenocarcinoma. However, the predictive value of m6A-related …