The integrated stress response (ISR) triggered in response to various cellular stress enables
mammalian cells to effectively cope with diverse stressful conditions while maintaining their …

Polyphenols and their derivates, a kind of natural product distributed in herb plants,
vegetables, and fruits, are the most abundant antioxidants in the human diet and have been …

Eukaryotic initiation factor 2B, eIF2B is a guanine nucleotide exchange, factor with a central
role in coordinating the initiation of translation. During stress and disease, the activity of …

In tumourigenesis, oncogenes or dysregulated tumour suppressor genes alter the canonical
translation machinery leading to a reprogramming of the translatome that, in turn, promotes …

During their quest for growth, adaptation, and survival, cancer cells create a favorable
environment through the manipulation of normal cellular mechanisms. They increase …

Background and Purpose Endoplasmic reticulum (ER) stress triggers an adaptive response
in tumours which fosters cell survival and resilience to stress. Activation of the ER stress …

Mitochondria are double membrane-bound organelles the network morphology of which in
cells is shaped by opposing events of fusion and fission executed by dynamin-like GTPases …

Abstract Whereas cysteine dioxygenase 1 (CDO1) expression is lost due to its
hypermethylated promoter across a range of cancer types including gastric cancer (GC), its …

Abstract RNA-binding proteins (RBPs)-RNA networks have contributed to cancer
development. Circular RNAs (circRNAs) are considered as protein recruiters; nevertheless …

Background Both N6-methyladenosine (m6A) and ferroptosis-related genes are associated
with the prognosis of lung adenocarcinoma. However, the predictive value of m6A-related …